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Rejection of stable cultured allografts by active or passive (adoptive) immunization.通过主动或被动（过继）免疫排斥稳定培养的同种异体移植物。
Proc Natl Acad Sci U S A. 1982 Mar;79(5):1626-8. doi: 10.1073/pnas.79.5.1626.
2
Cell transfer studies on the persistence of homograft sensitivity in the mouse: the periodic redistribution of sensitised cells between the circulation and lymphoid tissues.
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Immunologic mechanisms of corneal allografts reconstituted from cultured allogeneic endothelial cells in an immune-privileged site.在免疫赦免部位由培养的同种异体内皮细胞重建的角膜同种异体移植物的免疫机制。
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Lymphocyte recruitment properties of regional lymph node or spleen cells during skin allograft rejection.皮肤同种异体移植排斥反应期间区域淋巴结或脾细胞的淋巴细胞募集特性。
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Do immunologically privileged sites require a functioning spleen?免疫赦免部位需要一个功能正常的脾脏吗？
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Homograft sensitivity in the mouse: the periodic redistribution of sensitised lymphoid cells.小鼠中的同种异体移植敏感性：致敏淋巴细胞的周期性再分布。
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The rapid rejection of allogeneic lymphocytes by a non-adaptive, cell-mediated mechanism (NK activity).通过非适应性细胞介导机制（自然杀伤细胞活性）对同种异体淋巴细胞的快速排斥。
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Studies on the reaction of host lymphoid system in homotransplantation. II. Autoradiographic observation of cell proliferation against the skin allografts using tritiated thymidine.同种移植中宿主淋巴系统反应的研究。II. 利用氚标记胸腺嘧啶核苷对同种皮肤移植的细胞增殖进行放射自显影观察。
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Mechanism of self-tolerance to endocrine tissue.对内分泌组织的自身耐受机制。
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The failure of a major histocompatibility antigen to stimulate a thyroid allograft reaction after culture in oxygen.一种主要组织相容性抗原在氧气中培养后未能刺激甲状腺同种异体移植反应。
J Exp Med. 1983 Mar 1;157(3):898-906. doi: 10.1084/jem.157.3.898.
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Mononuclear phagocytes: a major population of effector cells responsible for rejection of allografted tumor cells in mice.单核吞噬细胞：小鼠同种异体移植肿瘤细胞排斥反应中主要的效应细胞群体。
Proc Natl Acad Sci U S A. 1991 Feb 15;88(4):1526-30. doi: 10.1073/pnas.88.4.1526.

本文引用的文献

1
A search for the optimum conditions for culturing allografts before transplantation.寻找移植前同种异体移植物培养的最佳条件。
Clin Immunol Immunopathol. 1980 Mar;15(3):314-7. doi: 10.1016/0090-1229(80)90043-4.
2
Cells mediating graft rejection in the mouse. I. Lyt-1 cells mediate skin graft rejection.介导小鼠移植物排斥反应的细胞。I. Lyt-1细胞介导皮肤移植物排斥反应。
J Exp Med. 1981 May 1;153(5):1044-57. doi: 10.1084/jem.153.5.1044.
3
Allo-responsive T lymphocytes and their differentiation markers.同种异体反应性T淋巴细胞及其分化标志物。
Fed Proc. 1981 Apr;40(5):1466-70.
4
Active suppression in the maintenance of pancreatic islet allografts.胰腺胰岛同种异体移植维持中的主动抑制
Transplantation. 1981 Aug;32(2):156-8. doi: 10.1097/00007890-198108000-00015.
5
Reversal diabetes by islet transplantation: vulnerability of the established allograft.通过胰岛移植逆转糖尿病：已建立的同种异体移植物的脆弱性。
Science. 1981 Sep 11;213(4513):1261-2. doi: 10.1126/science.6791285.
6
Activation of transplant immunity: effect of donor leukocytes on thyroid allograft rejection.移植免疫的激活：供体白细胞对甲状腺同种异体移植排斥反应的影响。
Science. 1976 Jan 30;191(4225):385-8. doi: 10.1126/science.1082167.
7
Effect of organ culture on the survival of thyroid allografts in mice.器官培养对小鼠甲状腺同种异体移植存活的影响。
Transplantation. 1976 Aug;22(2):138-49. doi: 10.1097/00007890-197608000-00009.

通过主动或被动（过继）免疫排斥稳定培养的同种异体移植物。

Rejection of stable cultured allografts by active or passive (adoptive) immunization.

作者信息

Vesole D H, Dart G A, Talmage D W

出版信息

Proc Natl Acad Sci U S A. 1982 Mar;79(5):1626-8. doi: 10.1073/pnas.79.5.1626.

DOI:10.1073/pnas.79.5.1626
PMID:6951201
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC346028/
Abstract

Injection of live lymphoid cells of donor strain or immune cells of recipient strain resulted in rejection of previously stable cultured mouse thyroid allografts. The results are interpreted to indicate that a cultured graft is relatively ineffective in activating recipient lymphocytes but is capable of maintaining them in an activated state and serving as a target for them once they are activated.

摘要

注射供体品系的活淋巴细胞或受体品系的免疫细胞会导致先前稳定培养的小鼠甲状腺同种异体移植被排斥。这些结果被解释为表明培养的移植物在激活受体淋巴细胞方面相对无效，但能够使它们保持激活状态，并一旦它们被激活就作为它们的靶标。