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通过主动或被动(过继)免疫排斥稳定培养的同种异体移植物。

Rejection of stable cultured allografts by active or passive (adoptive) immunization.

作者信息

Vesole D H, Dart G A, Talmage D W

出版信息

Proc Natl Acad Sci U S A. 1982 Mar;79(5):1626-8. doi: 10.1073/pnas.79.5.1626.

Abstract

Injection of live lymphoid cells of donor strain or immune cells of recipient strain resulted in rejection of previously stable cultured mouse thyroid allografts. The results are interpreted to indicate that a cultured graft is relatively ineffective in activating recipient lymphocytes but is capable of maintaining them in an activated state and serving as a target for them once they are activated.

摘要

注射供体品系的活淋巴细胞或受体品系的免疫细胞会导致先前稳定培养的小鼠甲状腺同种异体移植被排斥。这些结果被解释为表明培养的移植物在激活受体淋巴细胞方面相对无效,但能够使它们保持激活状态,并一旦它们被激活就作为它们的靶标。

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