Hemoglobin AI in community care.

In order to investigate the potential usefulness of knowing the blood concentrations of HbAI in primary care, HbAI was measured in diabetic subjects attending a primary care centre. The values were compared with concentration of HbAI in a reference group on non-diabetics. The reference group had a mean value in HbAI of 7.6+/-0.1% with a tendency to increased values with advancing age. The diabetic subjects had a mean value in HbAI of 10.8+/-0.2%. Diabetics under good control had lower values (10.2+/-0.2%), than patients under poor control (12.0+/-0.2%) (p less than 0.001). There was a correlation (r=0.50, p less than 0.001) between HbAI and fasting blood glucose levels. It is concluded that determination of HbAI can be an aid in the control of diabetics in primary care. However, the method requires good technical management, and the results are most reliable when the same person analyses all samples. The objective in diabetic therapy in this respect should no doubt be to depress the concentrations of HbAI towards normal values.