糖尿病控制与循环糖化血红蛋白A1之间的关系

The relationship between the control of diabetes mellitus and circulating glycosylated haemoglobin A1.

作者信息

Stanton K G, Davis R E

出版信息

Aust N Z J Med. 1978 Aug;8(4):400-4. doi: 10.1111/j.1445-5994.1978.tb04910.x.

DOI:10.1111/j.1445-5994.1978.tb04910.x

Abstract

The mean glycosylated haemoglobin A1 level in 200 diabetics, 13.2%+/-2.6 (1SD), was nearly twice the level found in 100 non-diabetics, 7.42%+/-0.6 (1SD), and overlap between the two populations was minimal. Glycosylated haemoglobin A1 levels, fasting and two hour post-prandial blood glucose concentrations and 24 hour urinary glucose excretion were measured at intervals over a period of 12 weeks in six diabetics requiring stabilisation. A close correlation was found between glycosylated haemoglobin A1 levels and short term parameters of control.

摘要

200名糖尿病患者糖化血红蛋白A1的平均水平为13.2%±2.6（1标准差），几乎是非糖尿病患者（100名，7.42%±0.6，1标准差）的两倍，且两组人群之间的重叠最小。对6名需要稳定治疗的糖尿病患者在12周内定期测量糖化血红蛋白A1水平、空腹及餐后两小时血糖浓度以及24小时尿糖排泄量。发现糖化血红蛋白A1水平与短期控制参数之间存在密切相关性。