Seidenfeld S M, Sutker W L, Luby J P
JAMA. 1982 Sep 17;248(11):1348-50.
Fusobacterium necrophorum septicemia developed in five patients after an oropharyngeal infection. Four patients had sore throat or neck pain, and two had findings of jugular vein septic thrombophlebitis. Metastatic abscesses, including embolic pneumonia, empyema, septic arthritis, and osteomyelitis, also occurred. Four patients recovered and one died. Proper treatment requires recognition of the oropharyngeal source of the septicemia and its differentiation from endocarditis. Antibiotic therapy should be prolonged, and metastatic abscesses drained.
5例患者在口咽感染后发生坏死梭杆菌败血症。4例患者有咽痛或颈部疼痛，2例有颈静脉化脓性血栓性静脉炎表现。还出现了转移性脓肿，包括栓塞性肺炎、脓胸、化脓性关节炎和骨髓炎。4例患者康复，1例死亡。正确的治疗需要识别败血症的口咽来源并将其与心内膜炎相鉴别。抗生素治疗应延长，转移性脓肿应引流。
