Baric J M, Alman J E, Feldman R S, Chauncey H H
Oral Surg Oral Med Oral Pathol. 1982 Oct;54(4):424-9. doi: 10.1016/0030-4220(82)90389-9.
Oral leukoplakia, a potentially malignant lesion, has been associated with tobacco smoking, but few studies have investigated the influence of different products on lesion prevalence. In the current study 925 healthy male subjects from the Veterans Administration Dental Longitudinal Study were examined for lesion site and prevalence. The participants were grouped according to smoking status: nonsmokers, smokers of cigarettes, cigars, a pipe, cigars plus a pipe, or cigarettes plus another tobacco product. In addition, the amount of product smoked, presence of a removable partial denture, and age were examined to determine their relation to leukoplakia prevalence. The data indicated that cigar smokers had significantly fewer lesions than the other smoker groups and that persons smoking a pipe or a pipe plus cigars had the highest prevalence. Heavy cigarette smokers had significantly more palatal lesions than light to moderate cigarette smokers. While removable partial dentures did not appear to affect lesion prevalence significantly, older smokers, persons of 50 years and above, had a significantly higher prevalence than persons less than 50 years of age.
口腔白斑是一种潜在的恶性病变，与吸烟有关，但很少有研究调查不同烟草制品对病变患病率的影响。在当前研究中，对来自退伍军人管理局牙科纵向研究的925名健康男性受试者进行了病变部位和患病率检查。参与者根据吸烟状况分组：不吸烟者、吸香烟者、吸雪茄者、抽烟斗者、吸雪茄加抽烟斗者，或吸香烟加另一种烟草制品者。此外，还检查了吸烟量、可摘局部义齿的佩戴情况和年龄，以确定它们与白斑患病率的关系。数据表明，吸雪茄者的病变明显少于其他吸烟组，而抽烟斗者或抽烟斗加吸雪茄者的患病率最高。重度吸烟者的腭部病变明显多于轻度至中度吸烟者。虽然可摘局部义齿似乎对病变患病率没有显著影响，但年龄较大的吸烟者（50岁及以上）的患病率明显高于50岁以下的人。
