Nakasima A, Ichinose M, Nakata S, Takahama Y
Am J Orthod. 1982 Aug;82(2):150-6. doi: 10.1016/0002-9416(82)90493-6.
We attempted to assess the role of heredity in the development of Angle's Class II and Class III malocclusions by comparing craniofacial morphologic differences between parents with Class II offspring and those with Class III offspring and by analyzing the parent-offspring correlations within each Class II and Class III malocclusion group. Lateral and frontal roentgenographic cephalograms were obtained for ninety-six patients with Class II malocclusion, 104 patients with Class III malocclusion, and their respective parents. Mean cephalometric profile diagrams were superimposed between the two groups of parents as well as between their offspring. Within the two groups, the parent-offspring correlation coefficients were computed for nineteen variables connecting cephalometric landmarks. The differences in the craniofacial complex were evident in the two groups of parents as well as in their offspring. High correlation coefficient values were seen between parents and their offspring in the Class II and Class III groups. Thus, there appears to be a strong familial tendency in the development of Class II and Class III malocclusions. We conclude that the hereditary pattern must be taken into consideration in the diagnosis and treatment of patients with these classes of malocclusion.
我们试图通过比较有安氏II类错（牙合）子女的父母与有安氏III类错（牙合）子女的父母之间的颅面形态差异，并分析每个安氏II类和III类错（牙合）组内的亲子相关性，来评估遗传在安氏II类和III类错（牙合）发育中的作用。对96例安氏II类错（牙合）患者、104例安氏III类错（牙合）患者及其各自的父母拍摄了头颅侧位片和正位片。两组父母之间以及他们的子女之间叠加了平均头影测量轮廓图。在两组中，计算了连接头影测量标志点的19个变量的亲子相关系数。颅面复合体的差异在两组父母及其子女中都很明显。在安氏II类和III类组中，父母与子女之间观察到高相关系数值。因此，安氏II类和III类错（牙合）的发育似乎有很强的家族倾向。我们得出结论，在诊断和治疗这些类别的错（牙合）患者时，必须考虑遗传模式。
