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胸腺细胞和T淋巴细胞的细胞化学研究。

Cytochemical study of thymocytes and T lymphocytes.

作者信息

Basso G, Cocito M G, Semenzato G, Pezzutto A, Zanesco L

出版信息

Br J Haematol. 1980 Apr;44(4):577-82. doi: 10.1111/j.1365-2141.1980.tb08712.x.

DOI:10.1111/j.1365-2141.1980.tb08712.x
PMID:6966508
Abstract

Fetal and postnatal thymocytes and circulating T lymphocytes were evaluated for six cytochemical reactions. Acid phosphatase activity was present in a high percentage of cells in all threee groups. Beta-glucoronidase and alpha-naphthyl acetate acid esterase were negative in the most immature fetal thymocytes, but become increasingly positive with T-cell maturation. Only the circulating lymphocytes presented a high percentage of N-acetyl beta glucosaminidase, alpha-naphthyl acetate esterase and alpha-naphthyl butyrate esterase positive cells. This study discusses the presence of these enzymes as proportional to different stages in T-cell maturation, and also of certain cytochemical phenotypes characteristic of these stages.

摘要

对胎儿和出生后胸腺细胞以及循环T淋巴细胞进行了六种细胞化学反应评估。酸性磷酸酶活性在所有三组细胞中的比例都很高。β-葡萄糖醛酸酶和α-萘乙酸酯酶在最不成熟的胎儿胸腺细胞中呈阴性,但随着T细胞成熟,其阳性率逐渐增加。只有循环淋巴细胞呈现出高比例的N-乙酰-β-葡萄糖苷酶、α-萘乙酸酯酶和α-萘丁酸酯酶阳性细胞。本研究讨论了这些酶的存在与T细胞成熟不同阶段的比例关系,以及这些阶段特有的某些细胞化学表型。

相似文献

1
Cytochemical study of thymocytes and T lymphocytes.胸腺细胞和T淋巴细胞的细胞化学研究。
Br J Haematol. 1980 Apr;44(4):577-82. doi: 10.1111/j.1365-2141.1980.tb08712.x.
2
The distribution of N-acetyl-beta-glucosaminidase, beta-glucuronidase, acid alpha-naphthyl acetate esterase and alpha-naphthyl acetate esterase in subpopulations of thymocytes, bone marrow cells and other lymphoid organs in mice.N-乙酰-β-葡糖胺酶、β-葡糖醛酸酶、酸性α-萘乙酸酯酶和α-萘乙酸酯酶在小鼠胸腺细胞、骨髓细胞及其他淋巴器官亚群中的分布
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3
Cytochemical reactions in resting and activated T-lymphocytes.静息和活化T淋巴细胞中的细胞化学反应。
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Cytochemical study in human lymphocyte subpopulations as defined by Fc receptors.对由Fc受体定义的人类淋巴细胞亚群进行细胞化学研究。
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Human medullary and cortical thymocytes are distinguishable according to the presence or absence of cytochemically demonstrable acid alpha-naphthyl acetate esterase (ANAE) activity.人类髓质和皮质胸腺细胞可根据细胞化学可显示的酸性α-萘乙酸酯酶(ANAE)活性的有无来区分。
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Cytochemical reactions of normal and neoplastic lymphocytes.正常及肿瘤性淋巴细胞的细胞化学反应
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Nonspecific esterase in human lymphocytes.人淋巴细胞中的非特异性酯酶
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引用本文的文献

1
Human T-cell malignancies: Correlative clinical, histopathologic, immunologic, and cytochemical analysis of 23 cases.人类T细胞恶性肿瘤:23例病例的临床、组织病理学、免疫学及细胞化学相关分析
Am J Pathol. 1982 Feb;106(2):187-203.
2
Correlation of lymphocyte beta-glucuronidase and N-acetyl-beta-glucosaminidase with E-rosette formation.淋巴细胞β-葡萄糖醛酸酶及N-乙酰-β-氨基葡萄糖苷酶与E-玫瑰花结形成的相关性
Histochem J. 1983 Feb;15(2):179-83. doi: 10.1007/BF01042286.
3
Ultrastructural cytochemistry of chronic T-cell leukaemias. A study with four acid hydrolases.
Histochem J. 1983 Sep;15(9):895-909. doi: 10.1007/BF01011828.
4
HNK-1 monoclonal antibody (Leu-7) in the identification of abnormal expansions of large granular lymphocytes.用于鉴定大颗粒淋巴细胞异常扩增的HNK-1单克隆抗体(Leu-7)
Clin Exp Immunol. 1983 Jun;52(3):641-7.
5
Cytochemistry of lymphoid cells: a review of findings in the normal and leukaemic state.淋巴细胞的细胞化学:正常及白血病状态下的研究结果综述
Histochem J. 1984 Oct;16(10):1027-50. doi: 10.1007/BF01002893.
6
Beta-glucuronidase activity in human T and B lymphocytes and the Tmu and T gamma subpopulations.人T淋巴细胞、B淋巴细胞以及Tmu和Tγ亚群中的β-葡萄糖醛酸酶活性。
Histochemistry. 1984;81(3):287-90. doi: 10.1007/BF00495641.
7
Ultrastructural patterns of the alpha-naphthyl butyrate esterase activity in normal and leukaemic peripheral blood leucocytes.正常及白血病外周血白细胞中丁酸α-萘酯酶活性的超微结构模式
Histochem J. 1985 May;17(5):595-604. doi: 10.1007/BF01003199.
8
Distribution pattern of acid phosphatase activity in human peripheral blood leukocytes: a cytochemical scanning electron microscopy study.人外周血白细胞酸性磷酸酶活性的分布模式:一项细胞化学扫描电子显微镜研究。
Histochemistry. 1990;94(3):315-21. doi: 10.1007/BF00266634.