妊娠特异性β1糖蛋白（SP1）的两种分子变体SP1α和SP1β的免疫化学与生物学研究。

Immunochemical and biological studies on two molecular variants of pregnancy specific beta 1 glycoprotein (SP1) SP1 alpha and SP1 beta.

作者信息

Grudzinskas J G, Teisner B, Al-Ani A T, Folkersen J, Westergaard J G, Chard T

出版信息

Clin Chim Acta. 1980 Sep 8;106(1):1-7. doi: 10.1016/0009-8981(80)90368-x.

Abstract

Analytical crossed immunoelectrophoresis was performed to examine the relationship of a high molecular mass alpha 2 mobile glycoprotein (SP1 alpha) which is immunochemically identifiable with pregnancy specific beta 1 glycoprotein (SP1 beta). There was no evidence for any reaction of SP1 alpha with antisera to normal human serum protein, nor for complex formation following incubation with normal serum proteins. The half-life of SP1 alpha was apparently shorter than that of SP1 beta after delivery of the placenta.

摘要

进行分析性交叉免疫电泳以研究一种高分子量α2移动糖蛋白（SP1α）与妊娠特异性β1糖蛋白（SP1β）在免疫化学上可识别的关系。没有证据表明SP1α与正常人血清蛋白抗血清有任何反应，也没有证据表明与正常血清蛋白孵育后会形成复合物。胎盘娩出后，SP1α的半衰期明显短于SP1β。