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重症肌无力的临床与免疫学关联。1:自身抗体。

Clinical and immunological associations in myasthenia gravis. 1: Autoantibodies.

作者信息

Sagar H J, Gelsthorpe K, Milford-Ward A, Davies-Jones G A

出版信息

J Neurol Neurosurg Psychiatry. 1980 Nov;43(11):967-70. doi: 10.1136/jnnp.43.11.967.

Abstract

Associations between female sex, HLA B8, positive anti-thyroid microsomal antibody and, to a lesser extent, antinuclear antibody were seen in 34 patients with myasthenia gravis. This supports the concept that the disease is heterogeneous. Anti-DNA antibodies, which were present in 62% of the patients, did not show such associations.

摘要

在34例重症肌无力患者中,发现女性、HLA B8、抗甲状腺微粒体抗体阳性之间存在关联,抗核抗体在一定程度上也存在关联。这支持了该疾病具有异质性的概念。62%的患者存在抗DNA抗体,但未显示出此类关联。

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