重症肌无力的临床与免疫学关联。2. 细胞介导免疫
Clinical and immunological associations in myasthenia gravis. 2. Cell-mediated immunity.
作者信息
Sagar H J, Davies-Jones G A, Allonby I D
出版信息
J Neurol Neurosurg Psychiatry. 1980 Nov;43(11):971-7. doi: 10.1136/jnnp.43.11.971.
Abstract
Myasthenic patients showed low absolute T cell counts and low spontaneous and phytohaemagglutinin-induced lymphocyte transformation responses. The abnormalities were particularly associated with late onset disease and female sex, but not with HLA phenotype or autoantibody production. Serum factors inhibitory to lymphocyte transformation occurred in some patients.
摘要
重症肌无力患者表现出绝对T细胞计数低，以及自发和植物血凝素诱导的淋巴细胞转化反应低下。这些异常尤其与晚发型疾病和女性性别相关，但与HLA表型或自身抗体产生无关。部分患者存在抑制淋巴细胞转化的血清因子。
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The establishment of a normal human population dose-response curve for lymphocytes cultured with PHA (phytohaemagglutinin).用植物血凝素（PHA）培养淋巴细胞的正常人群剂量反应曲线的建立。
Clin Exp Immunol. 1971 Mar;8(3):421-5.
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Immunologic studies of thymectomized and nonthymectomized patients with myasthenia gravis.对行胸腺切除术和未行胸腺切除术的重症肌无力患者的免疫学研究。
Ann N Y Acad Sci. 1966 Jan 26;135(1):536-54. doi: 10.1111/j.1749-6632.1966.tb45501.x.
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The pathology of the thymus gland in myasthenia gravis.重症肌无力患者胸腺的病理学表现。
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