Laing R A, Leibowitz H M, Oak S S, Chang R, Berrospi A R, Theodore J
Arch Ophthalmol. 1981 Jan;99(1):80-3. doi: 10.1001/archopht.1981.03930010082007.
The progressive morphological changes of cornea guttata in Fuchs' endothelial dystrophy have been characterized by clinical specular photomicroscopy. Five specific stages in the development of excrescences can be discerned using this in vivo technique. Several stages can be observed in the same cornea at a given time, although in most cases the majority of guttate changes seemed to have progressed to the same stage of development. All five stages of cornea guttata discerned in this study can occur in a cornea clinically free of edema. Two types of cornea guttata can be identified in vivo. One has a smooth, regular posterior surface, whereas the posterior contour of the second is irregular.
通过临床镜面显微镜检查已对富克斯内皮营养不良中角膜滴状病变的渐进性形态学变化进行了表征。使用这种体内技术可以识别出赘生物发展的五个特定阶段。在给定时间,同一角膜中可观察到几个阶段,尽管在大多数情况下,大多数滴状变化似乎已发展到相同的发育阶段。本研究中识别出的角膜滴状病变的所有五个阶段都可能发生在临床上无水肿的角膜中。在体内可以识别出两种类型的角膜滴状病变。一种后表面光滑、规则,而另一种的后轮廓不规则。