Croizat H, Frindel E
Exp Hematol. 1980 Feb;8(2):185-91.
Data reported in this paper show that a long range stimulating factor is released by irradiated bone marrow 15 minutes after exposure and that the secretion of the factor precedes CFUs proliferation. The factor seems to be elaborated by liver cells as is demonstrated by dose effect experiments as well as by the fact that protected bone marrow secretes a factor, albeit with different kinetics of secretion from those of irradiated bone marrow. The liberation of the factor seems to be regulated by the size of the stem cell compartment.
本文报道的数据表明，照射后的骨髓在暴露15分钟后会释放一种远距离刺激因子，且该因子的分泌先于集落形成单位（CFUs）的增殖。剂量效应实验以及受保护的骨髓分泌一种因子（尽管其分泌动力学与照射后的骨髓不同）这一事实表明，该因子似乎是由肝细胞产生的。因子的释放似乎受干细胞池大小的调节。
