Lom-Orta H, Alarcon-Segovia D, Diaz-Jouanen E
J Rheumatol. 1980 Nov-Dec;7(6):831-7.
We compared 31 patients who did, and 31 patients who did not, fulfill 4 or more criteria for the classification of systemic lupus erythematosus (SLE) at the time of diagnosis. Twenty-one of the latter 31 patients eventually developed enough manifestations to fulfill classification criteria. Ten never did despite average follow-up of 41 months. Patients who did not fulfill criteria at the time of diagnosis frequently had more thrombocytopenia and/or hemolytic anemia and continued to have fewer manifestations during the course of their disease than those who did. Failure to include this subject of SLE in studies with series of SLE patients may give a distorted picture of the disease.
我们比较了31例在诊断时符合4条或更多系统性红斑狼疮（SLE）分类标准的患者，以及31例不符合这些标准的患者。后31例患者中有21例最终出现了足够多的表现，从而符合分类标准。尽管平均随访了41个月，但另外10例患者从未达到标准。在诊断时不符合标准的患者比符合标准的患者更常出现血小板减少和/或溶血性贫血，并且在疾病过程中出现的症状也更少。在SLE患者系列研究中未纳入这一SLE主题，可能会使对该疾病的描述出现偏差。
