Borgström G H, Teerenhovi L, Vuopio P, Andersson L C, Knuutila S, Elonen E, de la Chapelle A
Scand J Haematol. 1981 Mar;26(3):241-51. doi: 10.1111/j.1600-0609.1981.tb01652.x.
Chromosome banding studies of the bone marrow were performed in 35 adult (greater than 14 years) patients with acute lymphoblastic leukaemia (ALL). Surface marker analysis was done in 24 of these and revealed 4 B-ALL, 5 T-ALL and 15 non-T non-B ALL. Most patients were studied at diagnosis before any treatment. A clonal karyotypic abnormality was found in 16 patients (46 %) initially. A Philadelphia chromosome was found in 3 patients, all belonging to the non-T non-B group. 5 patients, who all had blast cells with morphologic characteristics of Burkitt type L, were found to have bone marrow cells with a 14q + marker chromosome. In at least 4 cases this was due to a t(8;14). The cytogenetic findings showed some correlation to the ALL subgroup, but not to the response to treatment or the prognosis.
对35例成年（大于14岁）急性淋巴细胞白血病（ALL）患者进行了骨髓染色体显带研究。其中24例进行了表面标志物分析，结果显示4例B-ALL、5例T-ALL和15例非T非B-ALL。大多数患者在诊断时未经任何治疗即接受研究。最初在16例患者（46%）中发现克隆性核型异常。3例患者发现有费城染色体，均属于非T非B组。5例患者的原始细胞具有伯基特L型形态学特征，其骨髓细胞发现有14q +标记染色体。至少4例是由于t(8;14)。细胞遗传学结果显示与ALL亚组有一定相关性，但与治疗反应或预后无关。
