Biochemical and immunological characterization of the major envelope glycoprotein of bovine leukemia virus.
作者信息
Devare S G, Stephenson J R
出版信息
J Virol. 1977 Aug;23(2):443-7. doi: 10.1128/JVI.23.2.443-447.1977.
Abstract
The major envelope glycoprotein of bovine leukemia virus was isolated by lectin-bound Sepharose and DEAE-cellulose column chromatography. This protein was shown to have a molecular weight of about 41,000 and to lack detectable immunological cross-reactivity with glycoproteins of other oncornaviruses. Sera obtained from 100% of cattle examined with clinically diagnosed lymphosarcoma contained high-titered antibody to 125I-labeled bovine leukemia virus glycoprotein, whereas sera from animals in a disease-free herd were antibody negative.
摘要
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