牛白血病病毒主要包膜糖蛋白的生化与免疫学特性
Biochemical and immunological characterization of the major envelope glycoprotein of bovine leukemia virus.
作者信息
Devare S G, Stephenson J R
出版信息
J Virol. 1977 Aug;23(2):443-7. doi: 10.1128/JVI.23.2.443-447.1977.
Abstract
The major envelope glycoprotein of bovine leukemia virus was isolated by lectin-bound Sepharose and DEAE-cellulose column chromatography. This protein was shown to have a molecular weight of about 41,000 and to lack detectable immunological cross-reactivity with glycoproteins of other oncornaviruses. Sera obtained from 100% of cattle examined with clinically diagnosed lymphosarcoma contained high-titered antibody to 125I-labeled bovine leukemia virus glycoprotein, whereas sera from animals in a disease-free herd were antibody negative.
摘要
通过凝集素结合的琼脂糖凝胶和二乙氨基乙基纤维素柱色谱法分离出牛白血病病毒的主要包膜糖蛋白。该蛋白的分子量约为41,000，并且与其他肿瘤病毒的糖蛋白缺乏可检测到的免疫交叉反应性。对临床诊断为淋巴肉瘤的所有受检牛（100%）采集的血清含有针对125I标记的牛白血病病毒糖蛋白的高滴度抗体，而来自无病牛群动物的血清抗体呈阴性。
相似文献
1
Biochemical and immunological characterization of the major envelope glycoprotein of bovine leukemia virus.牛白血病病毒主要包膜糖蛋白的生化与免疫学特性
J Virol. 1977 Aug;23(2):443-7. doi: 10.1128/JVI.23.2.443-447.1977.
2
A bovine thymic lymphosarcoma case showing a negative serological response to bovine leukemia virus antigens, in a herd with high incidence of enzootic bovine leukosis.在地方流行性牛白血病发病率高的牛群中，有一例牛胸腺淋巴肉瘤病例，该病例对牛白血病病毒抗原的血清学反应呈阴性。
Zentralbl Veterinarmed B. 1981;28(9-10):733-42. doi: 10.1111/j.1439-0450.1981.tb01801.x.
3
Bovine lymphosarcoma: development of a radioimmunologic technique for detection of the etiologic agent.牛淋巴肉瘤：一种用于检测病原体的放射免疫技术的开发
Science. 1976 Dec 24;194(4272):1428-30. doi: 10.1126/science.188129.
4
Inhibition of bovine leukemia virus release.牛白血病病毒释放的抑制作用。
J Natl Cancer Inst. 1975 May;54(5):1199-202. doi: 10.1093/jnci/54.5.1199.
5
Proteins of bovine leukemia virus. I. Characterization and reactions with natural antibodies.牛白血病病毒的蛋白质。I. 特性及与天然抗体的反应
J Virol. 1977 Mar;21(3):1056-60. doi: 10.1128/JVI.21.3.1056-1060.1977.
6
7
8
9
Bovine leukosis in Nigeria--a preliminary study.尼日利亚的牛白血病——一项初步研究。
Bull Anim Health Prod Afr. 1981 Sep;29(3):255-8.
10
Bovine and ovine leukemia viruses. I. Characterization of viral antigens.牛和绵羊白血病病毒。I.病毒抗原的特性
J Virol. 1978 Apr;26(1):159-64. doi: 10.1128/JVI.26.1.159-164.1978.
引用本文的文献
1
Monoclonal antibodies against human factor VIII molecular neutralize antihemophilic factor and ristocetin cofactor activities.针对人凝血因子 VIII 分子的单克隆抗体可中和抗血友病因子和瑞斯托霉素辅因子活性。
Proc Natl Acad Sci U S A. 1982 Jan;79(1):183-7. doi: 10.1073/pnas.79.1.183.
2
Monoclonal antibodies to the transformation-specific glycoprotein encoded by the feline retroviral oncogene v-fms.针对猫逆转录病毒癌基因v-fms编码的转化特异性糖蛋白的单克隆抗体。
J Virol. 1982 Nov;44(2):696-702. doi: 10.1128/JVI.44.2.696-702.1982.
3
Binding characteristics of wild mouse type C virus to mouse spinal cord and spleen cells.野生小鼠C型病毒与小鼠脊髓和脾细胞的结合特性。
Infect Immun. 1982 Aug;37(2):532-8. doi: 10.1128/iai.37.2.532-538.1982.
4
Evidence that the spontaneous blastogenesis of lymphocytes from bovine leukemia virus-infected cattle is viral antigen specific.来自感染牛白血病病毒的牛的淋巴细胞自发增殖是病毒抗原特异性的证据。
Infect Immun. 1981 Oct;34(1):84-9. doi: 10.1128/iai.34.1.84-89.1981.
5
Transformed phenotypes in long-term cultures persistently infected with bovine leukemia virus.长期感染牛白血病病毒的培养物中的转化表型持续存在。
Can J Comp Med. 1981 Apr;45(2):154-8.
6
Type-specific radioimmunoassays for the gp70s of mink cell focus-inducing murine leukemia viruses: expression of a cross-reacting antigen in cells infected with the Friend strain of the spleen focus-forming virus.水貂细胞集落诱导型小鼠白血病病毒gp70的型特异性放射免疫测定：脾脏集落形成病毒Friend株感染细胞中一种交叉反应抗原的表达
J Exp Med. 1978 Sep 1;148(3):654-63. doi: 10.1084/jem.148.3.654.
7
Morphological revertants of an avian sarcoma virus-transformed mammalian cell line exhibit tumorigenicity and contain pp60src.一种禽肉瘤病毒转化的哺乳动物细胞系的形态学回复突变体具有致瘤性并含有pp60src。
Proc Natl Acad Sci U S A. 1979 Aug;76(8):3904-8. doi: 10.1073/pnas.76.8.3904.
8
Amino-terminal sequence of bovine leukemia virus major internal protein: homology with mammalian type C virus p30 structural proteins.牛白血病病毒主要内部蛋白的氨基末端序列：与哺乳动物C型病毒p30结构蛋白的同源性
Proc Natl Acad Sci U S A. 1979 Jun;76(6):2996-3000. doi: 10.1073/pnas.76.6.2996.
9
Bovine and ovine leukemia viruses. I. Characterization of viral antigens.牛和绵羊白血病病毒。I.病毒抗原的特性
J Virol. 1978 Apr;26(1):159-64. doi: 10.1128/JVI.26.1.159-164.1978.
10
Feline leukemia virus: biochemical and immunological characterization of gag gene-coded structural proteins.猫白血病病毒：gag基因编码的结构蛋白的生化及免疫学特性
J Virol. 1977 Sep;23(3):599-607. doi: 10.1128/JVI.23.3.599-607.1977.
本文引用的文献
1
PEDIGREE STUDIES IN BOVINE LYMPHOSARCOMA.牛淋巴肉瘤的谱系研究
Ann N Y Acad Sci. 1963 Nov 4;108:1193-202. doi: 10.1111/j.1749-6632.1963.tb13444.x.
2
Cleavage of structural proteins during the assembly of the head of bacteriophage T4.在噬菌体T4头部组装过程中结构蛋白的切割
Nature. 1970 Aug 15;227(5259):680-5. doi: 10.1038/227680a0.
3
Immunochemical characterization of two major polypeptides from murine mammary tumor virus.小鼠乳腺肿瘤病毒两种主要多肽的免疫化学特性分析
J Virol. 1974 Jun;13(6):1200-10. doi: 10.1128/JVI.13.6.1200-1210.1974.
4
The polypeptide composition of mouse mammary tumor virus.小鼠乳腺肿瘤病毒的多肽组成。
Virology. 1974 Apr;58(2):387-95. doi: 10.1016/0042-6822(74)90074-9.
5
Immunological characterization of a low molecular weight polypeptide of murine leukemia virus.小鼠白血病病毒一种低分子量多肽的免疫学特性
Virology. 1973 Jul;54(1):199-206. doi: 10.1016/0042-6822(73)90129-3.
6
Properties of mouse leukemia viruses. VIII. The major viral glycoprotein of Friend leukemia virus. Seroimmunological, interfering and hemagglutinating capacities.小鼠白血病病毒的特性。VIII. 弗瑞德白血病病毒的主要病毒糖蛋白。血清免疫学、干扰及血凝能力。
Virology. 1974 Dec;62(2):307-18. doi: 10.1016/0042-6822(74)90394-8.
7
Biological expression of antigenic determinants of murine leukemia virus proteins gp69-71 and p30.鼠白血病病毒蛋白gp69 - 71和p30抗原决定簇的生物学表达
J Virol. 1974 Nov;14(5):1274-80. doi: 10.1128/JVI.14.5.1274-1280.1974.
8
Structural proteins of mammalian oncogenic RNA viruses: murine leukemia virus neutralization by antisera prepared against purified envelope glycoprotein.哺乳动物致癌RNA病毒的结构蛋白：用针对纯化包膜糖蛋白制备的抗血清对小鼠白血病病毒进行中和
J Virol. 1974 Jul;14(1):187-9. doi: 10.1128/JVI.14.1.187-189.1974.
9
Structural proteins of mammalian oncogenic RNA viruses: multiple antigenic determinants of the major internal protein and envelope glycoprotein.哺乳动物致癌RNA病毒的结构蛋白：主要内部蛋白和包膜糖蛋白的多种抗原决定簇。
J Virol. 1974 Jan;13(1):171-80. doi: 10.1128/JVI.13.1.171-180.1974.
10
Mason-Pfizer virus RNA genome: relationship to the RNA of morphologically similar isolates and other oncornaviruses.梅森-辉瑞病毒RNA基因组：与形态学相似分离株的RNA及其他肿瘤病毒RNA的关系。
J Virol. 1976 Mar;17(3):705-12. doi: 10.1128/JVI.17.3.705-712.1976.
Zotero 插件