[Chromatographic method on a thin sorbent layer for studying the purity and quality of the antitumor antibiotic, rubomycin].
作者信息
Pokras L S, Snezhnova L P, Brazhnikova M G, Grigor'eva V M
出版信息
Antibiotiki. 1978 Sep;23(9):788-92.
PMID:697337
Abstract
A method for qualitative and quantitative investigation of rubomycin composition was developed. It was based on chromatographic separation of the antibiotic components in a thin layer of silicic acid followed by their elution and spectrophotometric determination. An additional component of rubomycin found in the therapeutic preparations and the conditions of its formation were studied. Fifteen different lots of rubomycin were assayed and the requirements for the limits of the admixtures in the antibiotic therapeutic preparations were determined.
摘要
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