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新城疫副粘病毒对恶唑酮接触敏感性的抑制作用。感染性病毒对介导接触性反应的效应T细胞的损害作用。

Depression of contact sensitivity to oxazolone by the paramyxovirus of Newcastle disease. Impairment by infectious virus of effector T cells which mediate the response to contactant.

作者信息

Caruso C, Palmeri P, Dieli F, Bellina L, Benvegna S, Cillari E, Salerno A

出版信息

Int Arch Allergy Appl Immunol. 1981;66(1):91-9. doi: 10.1159/000232804.

DOI:10.1159/000232804
PMID:6973547
Abstract

The paramyxovirus of Newcastle disease (NDV) impairs the contact sensitivity to oxazolone in CBA/J mice: in vitro treatment with the infectious virus inhibits the passive transfer of contact sensitivity. Experiments performed with three different virus preparations demonstrate that only the infectious virus is able to inhibit the hypersensitivity reaction while treatment of virus by heat or ultraviolet irradiation wipes out its inhibitory activity. These results suggest that I-NDV depresses the response to oxazolone by its action on T immunoblasts which mediate the response to contactant.

摘要

新城疫副粘病毒(NDV)会削弱CBA/J小鼠对恶唑酮的接触敏感性:用感染性病毒进行体外处理会抑制接触敏感性的被动转移。使用三种不同病毒制剂进行的实验表明,只有感染性病毒能够抑制超敏反应,而通过加热或紫外线照射处理病毒会消除其抑制活性。这些结果表明,I-NDV通过作用于介导对接触剂反应的T免疫母细胞来抑制对恶唑酮的反应。

相似文献

1
Depression of contact sensitivity to oxazolone by the paramyxovirus of Newcastle disease. Impairment by infectious virus of effector T cells which mediate the response to contactant.新城疫副粘病毒对恶唑酮接触敏感性的抑制作用。感染性病毒对介导接触性反应的效应T细胞的损害作用。
Int Arch Allergy Appl Immunol. 1981;66(1):91-9. doi: 10.1159/000232804.
2
Depression of contact hypersensitivity to oxazolone in mice exposed to Newcastle disease virus.感染新城疫病毒的小鼠对恶唑酮接触性超敏反应的抑制
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引用本文的文献

1
Analysis of the T suppressor cell circuit which regulates contact sensitivity in mice infected with the virus of Newcastle disease.对感染新城疫病毒的小鼠中调节接触敏感性的T抑制细胞回路的分析。
Immunology. 1984 Feb;51(2):305-11.
2
Induction and Ly phenotype of suppressor T cells in mice during primary infection with dengue virus.登革病毒初次感染小鼠期间抑制性T细胞的诱导及Ly表型
Immunology. 1984 Jan;51(1):51-6.
3
Inhibition of lymphocyte mitogenesis in mice infected with Newcastle disease virus: viral interference with the interleukin system.
新城疫病毒感染小鼠中淋巴细胞有丝分裂的抑制:病毒对白介素系统的干扰
Immunology. 1986 Mar;57(3):373-8.
4
Impairment of contrasuppressor activity in mice infected with the paramyxovirus of Newcastle disease.感染新城疫副粘病毒的小鼠中抗抑制因子活性受损。
Immunology. 1992 Feb;75(2):245-9.