辅助性T细胞对流感病毒细胞毒性T淋巴细胞反应的特异性。
Specificity of the helper T cell for the cytolytic T lymphocyte response to influenza viruses.
作者信息
Reiss C S, Burakoff S J
出版信息
J Exp Med. 1981 Aug 1;154(2):541-6. doi: 10.1084/jem.154.2.541.
Abstract
We have described a model system in which helper T cells are required to mount a primary antiviral cytolytic T lymphocyte response. The radioresistant helper cell can be found in the spleens of mice that have been immunized subcutaneously with influenza viruses 6-8 d previously. These helper cells appear to be type specific but cross-reactive among the subtypes of influenza A viruses. The phenotypes of the interacting cell populations were determined.
摘要
我们已经描述了一个模型系统，在该系统中，辅助性T细胞对于启动原发性抗病毒细胞毒性T淋巴细胞反应是必需的。在6-8天前经皮下用流感病毒免疫的小鼠脾脏中可发现抗辐射辅助细胞。这些辅助细胞似乎具有型特异性，但在甲型流感病毒的亚型之间具有交叉反应性。确定了相互作用细胞群体的表型。
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