T 细胞区淋巴瘤的细胞遗传学发现。
Cytogenetic findings in T-zone lymphoma.
作者信息
Gödde-Salz E, Schwarze E W, Stein H, Lennert K, Grote W
出版信息
J Cancer Res Clin Oncol. 1981;101(1):81-9. doi: 10.1007/BF00405068.
Abstract
Five cases of T-zone lymphoma were investigated with histologic, immunologic, and cytogenetic methods. The chromosome analyses were performed on lymphoma cells prepared immediately after removal of the lymph nodes. The chromosomes involved in structural rearrangements were nos. 1, 2, 3, 4, 14, and Y. Numbers 3, 5, 6, and 13 were lost by some tumors, and nos. 3 and 9 were gained. Chromosome 3 was involved most often in structural and numerical aberrations, whereas 14q + markers occurred in only one case. The importance of multidisciplinary studies is pointed out.
摘要
采用组织学、免疫学和细胞遗传学方法对5例T区淋巴瘤进行了研究。染色体分析是在切除淋巴结后立即制备的淋巴瘤细胞上进行的。发生结构重排的染色体为1、2、3、4、14和Y号染色体。一些肿瘤丢失了3、5、6和13号染色体，获得了3和9号染色体。3号染色体最常发生结构和数量异常，而14q +标记仅在1例中出现。指出了多学科研究的重要性。
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