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新生儿中的B淋巴细胞。

B lymphocytes in newborns.

作者信息

Agostini C, Colombatti M, Sanzari M, Gasparotto G, Piovesan A, Rubaltelli F F, Semenzato G

出版信息

Arch Immunol Ther Exp (Warsz). 1981;29(1):79-84.

PMID:6974546
Abstract

B lymphocyte markers in 24 full term newborn infants were evaluated within four days after birth. It was demonstrated that the percentage of cells with surface immunoglobulins (SmIg) in the blood of these subjects was normal when the lymphocytes were stained with polyvalent as well as monospecific antisera. The percentage of cells bearing Fc receptors were found to be slightly, but not significantly, reduced. The ability of newborn lymphocytes to form rosettes with mouse erythrocytes was significantly reduced. The hypothesis that the B dependent system reaches complete maturity already at the first days after birth is discussed.

摘要

对24名足月新生儿出生后4天内的B淋巴细胞标志物进行了评估。结果表明,当用多价及单特异性抗血清对淋巴细胞进行染色时,这些受试者血液中具有表面免疫球蛋白(SmIg)的细胞百分比正常。发现带有Fc受体的细胞百分比略有降低,但不显著。新生儿淋巴细胞与小鼠红细胞形成玫瑰花结的能力显著降低。文中讨论了B依赖系统在出生后第一天就已完全成熟的假说。

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