Spira W M, Khan M U, Saeed Y A, Sattar M A
Bull World Health Organ. 1980;58(5):731-40.
The apparent failure of handpump tubewells to reduce the incidence of cholera among users in the flooded rural area of Bangladesh has stimulated interest in defining precisely the means of Vibrio cholerae transmission during localized outbreaks. Cholera-infected neighbourhoods were placed under intensive microbiological surveillance to pinpoint contaminated sources and subsequent infections. The results show that cholera transmission was via contaminated surface water, particularly water taken into households for cooking or drinking. Infections resulted from a daily dose not exceeding 10(5) organisms and the frequency of exposure appeared to be a major determinant of the infection rate. The importance of these data in environmental interventions and particularly in the provision of tubewells is discussed.
在孟加拉国洪水泛滥的农村地区,手动泵管井未能降低使用者中霍乱的发病率,这一明显的失败引发了人们对于精确界定霍乱弧菌在局部暴发期间传播途径的兴趣。对霍乱感染的社区进行了强化微生物监测,以查明受污染的源头及随后发生的感染情况。结果表明,霍乱是通过受污染的地表水传播的,尤其是进入家庭用于烹饪或饮用的水。每日摄入不超过10⁵个菌体就会导致感染,而且接触频率似乎是感染率的一个主要决定因素。文中讨论了这些数据在环境干预措施中,尤其是在提供管井方面的重要性。