Lucivero G, Lawton A R, Cooper M D
Clin Exp Immunol. 1981 Jul;45(1):185-90.
Our studies indicate that rosette formation with mouse erythrocytes defines a subpopulation of human B lymphocytes positive for both sIgM, sIgD and C3 receptors but largely negative for IgG Fc receptors. These cells respond very poorly to PWM stimulation, even when reconstituted in culture with optimal numbers of autologous T cells and adherent cells.
我们的研究表明,与小鼠红细胞形成玫瑰花结可定义出人类B淋巴细胞的一个亚群,该亚群对sIgM、sIgD和C3受体均呈阳性,但对IgG Fc受体大多呈阴性。这些细胞对PWM刺激反应很差,即便在培养中用最适宜数量的自体T细胞和贴壁细胞进行重建时也是如此。