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引起儿童全身性感染的流感嗜血杆菌的血清型及氨苄西林敏感性:3年经验总结

Serotype and ampicillin susceptibility of Haemophilus influenzae causing systemic infections in children: 3 years of experience.

作者信息

Mason E O, Kaplan S L, Lamberth L B, Hinds D B, Kvernland S J, Loiselle E M, Feigin R D

出版信息

J Clin Microbiol. 1982 Apr;15(4):543-6. doi: 10.1128/jcm.15.4.543-546.1982.

Abstract

Over a 3-year period, 96% of systemic infections in children caused by Haemophilus influenzae were of serotype b. Of 346 invasive infections, 15 (4%) were caused by non-type b H. influenzae. The monthly prevalence of ampicillin resistance in all isolates was highly variable (0 to 63%). Ampicillin resistance in H. influenzae causing invasive disease occurred in 13% of non-type b and 21.8% of type b isolates. There was no significant difference (x2 - 0.21; p greater than 0.10) in the rate of ampicillin resistance between type b and non-type b H. influenzae causing systemic illness in children over a 3-year period.

摘要

在3年期间,由流感嗜血杆菌引起的儿童全身性感染中,96%为b型血清型。在346例侵袭性感染中,15例(4%)由非b型流感嗜血杆菌引起。所有分离株中氨苄西林耐药的月度患病率变化很大(0%至63%)。引起侵袭性疾病的流感嗜血杆菌中,非b型分离株的氨苄西林耐药率为13%,b型分离株为21.8%。在3年期间,引起儿童全身性疾病的b型和非b型流感嗜血杆菌之间,氨苄西林耐药率没有显著差异(卡方值 = 0.21;p大于0.10)。

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