一种支原体促细胞分裂剂对来自人类和各种动物宿主淋巴细胞的特异性。
Specificity of a mycoplasma mitogen for lymphocytes from human and various animal hosts.
作者信息
Cole B C, Washburn L R, Sullivan G J, Ward J R
出版信息
Infect Immun. 1982 May;36(2):662-6. doi: 10.1128/iai.36.2.662-666.1982.
Abstract
Spleen lymphocytes from Lewis and Buffalo rats and peripheral blood lymphocytes from 10 human donors exhibited high levels of transformation when exposed to Mycoplasma arthritidis supernatants. In contrast, spleen lymphocytes from rabbits and guinea pigs and peripheral blood lymphocytes from sheep and calves failed to transform when exposed to M. arthritidis supernatants. The lymphocytes from all hosts were transformed in the presence of phytohemagglutinin or concanavalin A or both Serological studies failed to provide evidence that the responding hosts were presensitized against M. arthritidis antigens.
摘要
当暴露于关节炎支原体上清液时，来自Lewis大鼠和布法罗大鼠的脾淋巴细胞以及来自10名人类供体的外周血淋巴细胞表现出高水平的转化。相比之下，来自兔子和豚鼠的脾淋巴细胞以及来自绵羊和小牛的外周血淋巴细胞在暴露于关节炎支原体上清液时未能发生转化。在存在植物血凝素或伴刀豆球蛋白A或两者的情况下，所有宿主的淋巴细胞都发生了转化。血清学研究未能提供证据表明反应宿主对关节炎支原体抗原预先致敏。
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Growth on artificial medium of an agent associated with atypical pneumonia and its identification as a PPLO.一种与非典型肺炎相关的病原体在人工培养基上的生长及其被鉴定为类胸膜肺炎微生物。
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