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一种支原体促细胞分裂剂对来自人类和各种动物宿主淋巴细胞的特异性。

Specificity of a mycoplasma mitogen for lymphocytes from human and various animal hosts.

作者信息

Cole B C, Washburn L R, Sullivan G J, Ward J R

出版信息

Infect Immun. 1982 May;36(2):662-6. doi: 10.1128/iai.36.2.662-666.1982.

DOI:10.1128/iai.36.2.662-666.1982
PMID:6979514
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC351280/
Abstract

Spleen lymphocytes from Lewis and Buffalo rats and peripheral blood lymphocytes from 10 human donors exhibited high levels of transformation when exposed to Mycoplasma arthritidis supernatants. In contrast, spleen lymphocytes from rabbits and guinea pigs and peripheral blood lymphocytes from sheep and calves failed to transform when exposed to M. arthritidis supernatants. The lymphocytes from all hosts were transformed in the presence of phytohemagglutinin or concanavalin A or both Serological studies failed to provide evidence that the responding hosts were presensitized against M. arthritidis antigens.

摘要

当暴露于关节炎支原体上清液时，来自Lewis大鼠和布法罗大鼠的脾淋巴细胞以及来自10名人类供体的外周血淋巴细胞表现出高水平的转化。相比之下，来自兔子和豚鼠的脾淋巴细胞以及来自绵羊和小牛的外周血淋巴细胞在暴露于关节炎支原体上清液时未能发生转化。在存在植物血凝素或伴刀豆球蛋白A或两者的情况下，所有宿主的淋巴细胞都发生了转化。血清学研究未能提供证据表明反应宿主对关节炎支原体抗原预先致敏。

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Specificity of a mycoplasma mitogen for lymphocytes from human and various animal hosts.一种支原体促细胞分裂剂对来自人类和各种动物宿主淋巴细胞的特异性。
Infect Immun. 1982 May;36(2):662-6. doi: 10.1128/iai.36.2.662-666.1982.
2
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本文引用的文献

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Effect of Animal Passage on Arthritogenic and Biological Properties of Mycoplasma arthritidis.动物 passage 对关节炎致病和生物学特性的影响。
Infect Immun. 1970 Jun;1(6):538-45. doi: 10.1128/iai.1.6.538-545.1970.
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Growth on artificial medium of an agent associated with atypical pneumonia and its identification as a PPLO.一种与非典型肺炎相关的病原体在人工培养基上的生长及其被鉴定为类胸膜肺炎微生物。
Proc Natl Acad Sci U S A. 1962 Jan 15;48(1):41-9. doi: 10.1073/pnas.48.1.41.
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Stimulation of mouse lymphocytes by a mitogen derived from Mycoplasma arthritidis. I. Transformation is associated with an H-2-linked gene that maps to the I-E/I-C subregion.关节炎支原体衍生的促细胞分裂剂对小鼠淋巴细胞的刺激作用。I. 转化与一个定位到I-E/I-C亚区的H-2连锁基因相关。
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Chronic arthritis of rabbits induced by mycoplasmas. II. Antibody response and the deposition of immune complexes.
Arthritis Rheum. 1980 Jul;23(7):837-45. doi: 10.1002/art.1780230710.
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Mycoplasma-dependent activation of normal mouse lymphocytes: requirement for functional T lymphocytes in the cytotoxicity reaction mediated by Mycoplasma arthritidis.支原体对正常小鼠淋巴细胞的激活：关节炎支原体介导的细胞毒性反应中功能性T淋巴细胞的需求。
Infect Immun. 1980 Oct;30(1):90-8. doi: 10.1128/iai.30.1.90-98.1980.
6
Mycoplasma-mediated activation of normal mouse lymphocytes: induction of cytotoxic lymphocytes and lymphocyte transformation by Mycoplasma arthritidis are under Ir gene control.支原体介导的正常小鼠淋巴细胞激活：关节炎支原体诱导的细胞毒性淋巴细胞和淋巴细胞转化受Ir基因控制。
J Immunol. 1981 Mar;126(3):922-7.
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Chronic proliferative arthritis of mice induced by Mycoplasma arthritidis. I. Induction of disease and histopathological characteristics.关节炎支原体诱导的小鼠慢性增殖性关节炎。I. 疾病诱导及组织病理学特征
Infect Immun. 1971 Oct;4(4):344-55. doi: 10.1128/iai.4.4.344-355.1971.
8
Isolation of mononuclear cells and granulocytes from human blood. Isolation of monuclear cells by one centrifugation, and of granulocytes by combining centrifugation and sedimentation at 1 g.从人血中分离单核细胞和粒细胞。通过一次离心分离单核细胞，通过离心和1g沉降相结合的方法分离粒细胞。
Scand J Clin Lab Invest Suppl. 1968;97:77-89.
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Induction of interferon in ovine and human lymphocyte cultures by mycoplasmas.支原体在绵羊和人类淋巴细胞培养物中诱导干扰素的产生。
Infect Immun. 1976 Jul;14(1):88-94. doi: 10.1128/iai.14.1.88-94.1976.
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Mycoplasma-dependent activation of normal lymphocytes: mitogenic potential of mycoplasmas for mouse lymphocytes.支原体对正常淋巴细胞的依赖性激活：支原体对小鼠淋巴细胞的促有丝分裂潜力。
Infect Immun. 1977 Nov;18(2):393-9. doi: 10.1128/iai.18.2.393-399.1977.