支原体在绵羊和人类淋巴细胞培养物中诱导干扰素的产生。
Induction of interferon in ovine and human lymphocyte cultures by mycoplasmas.
作者信息
Cole B C, Overall J C, Lombardi P S, Glasgow L A
出版信息
Infect Immun. 1976 Jul;14(1):88-94. doi: 10.1128/iai.14.1.88-94.1976.
Abstract
Mycoplasma pneumoniae, Acholeplasma laidlawii, M. arthritidis, and M. pulmonis were shown to induce interferon in the lymphocyte fraction of ovine peripheral blood leukocytes, but not in the polymorphonuclear leukocyte fraction. Human peripheral blood lymphocytes produced significant levels of interferon in response to infection with M. pneumoniae and M. synoviae. The antiviral substance induced by the mycoplasmas in human lymphocytes was characterized as interferon by the usual criteria.
摘要
肺炎支原体、莱氏无胆甾原体、关节炎支原体和肺支原体可在绵羊外周血白细胞的淋巴细胞部分诱导产生干扰素，但在多形核白细胞部分则不会。人外周血淋巴细胞在受到肺炎支原体和滑膜支原体感染时会产生显著水平的干扰素。支原体在人淋巴细胞中诱导产生的抗病毒物质根据通常标准被鉴定为干扰素。
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