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豚鼠皮内注射T细胞有丝分裂原后,其局部淋巴结中嗜碱性粒细胞浸润的精细结构。

Fine structures of the basophil infiltration in regional lymph nodes of the guinea-pig after the intradermal injection of T cell mitogens.

作者信息

Kimura M, Takaya K

出版信息

Experientia. 1982 May 15;38(5):621-2. doi: 10.1007/BF02327084.

DOI:10.1007/BF02327084
PMID:6980141
Abstract

Basophil-rich infiltrates in regional lymph nodes of guinea-pigs were demonstrated by electron microscopy after the intradermal injection of T cell mitogens (PHA and Con A). Basophils infiltrated the stroma of the lymph node via the postcapillary venules (PCV) and migrated to the paracortex. Prior to infiltration of the lymph nodes a cutaneous basophil hypersensitivity reaction was seen in the mitogen-injected skin. B cell mitogen (LPS) injection did not induce this response.

摘要

在豚鼠皮内注射T细胞有丝分裂原(PHA和Con A)后,通过电子显微镜观察到其局部淋巴结中有富含嗜碱性粒细胞的浸润。嗜碱性粒细胞通过毛细血管后微静脉(PCV)浸润淋巴结基质,并迁移至副皮质区。在淋巴结浸润之前,在注射有丝分裂原的皮肤中可见皮肤嗜碱性粒细胞超敏反应。注射B细胞有丝分裂原(LPS)未诱导出这种反应。

相似文献

1
Fine structures of the basophil infiltration in regional lymph nodes of the guinea-pig after the intradermal injection of T cell mitogens.豚鼠皮内注射T细胞有丝分裂原后,其局部淋巴结中嗜碱性粒细胞浸润的精细结构。
Experientia. 1982 May 15;38(5):621-2. doi: 10.1007/BF02327084.
2
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引用本文的文献

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Lymphatic mast cells in response to in vitro stimulation by non-specific T-cell mitogens.淋巴肥大细胞对非特异性T细胞有丝分裂原的体外刺激作出反应。
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本文引用的文献

1
Dynamic and morphological responses of draining lymph nodes to single and repeated applications of oxazolone to guinea-pig skin.豚鼠皮肤单次及重复应用恶唑酮后引流淋巴结的动态和形态学反应
Virchows Arch B Cell Pathol Incl Mol Pathol. 1980;33(2):155-65. doi: 10.1007/BF02899178.
2
Cutaneous basophil hypersensitivity. II. A light and electron microscopic description.皮肤嗜碱性粒细胞超敏反应。II. 光镜和电镜描述。
J Exp Med. 1970 Sep 1;132(3):558-82. doi: 10.1084/jem.132.3.558.
3
The kinetics of mast cells in lymph nodes of immunized mice.
免疫小鼠淋巴结中肥大细胞的动力学
Immunology. 1973 Jan;24(1):47-53.
4
The cutaneous basophil response to mitogens.皮肤嗜碱性粒细胞对丝裂原的反应。
J Immunol. 1974 Aug;113(2):496-500.
5
Chemotaxis of basophils by lymphocyte-dependent and lymphocyte-independent mechanisms.嗜碱性粒细胞通过淋巴细胞依赖和非淋巴细胞依赖机制的趋化作用。
J Immunol. 1975 May;114(5):1523-31.
6
Ultrastructure of basophilic leukocytes and mast cells in normal and cutaneous basophil hypersensitivity-reacted guinea pig dermis.正常及皮肤嗜碱性粒细胞超敏反应豚鼠真皮中嗜碱性白细胞和肥大细胞的超微结构
Int Arch Allergy Appl Immunol. 1979;60(4):383-9. doi: 10.1159/000232368.
7
Mechanisms of hypersensitivity: cellular interactions. Basophil arrival and function in tissue hypersensitivity reactions.超敏反应机制:细胞间相互作用。嗜碱性粒细胞在组织超敏反应中的抵达与功能。
J Allergy Clin Immunol. 1979 Aug;64(2):79-89. doi: 10.1016/0091-6749(79)90041-1.
8
Morphological and histochemical analyses of two human T-cell subpopulations bearing receptors for IgM or IgG.对两个带有IgM或IgG受体的人T细胞亚群进行的形态学和组织化学分析。
J Exp Med. 1978 May 1;147(5):1405-17. doi: 10.1084/jem.147.5.1405.
9
Functional anatomy of lymph nodes. I. The paracortical cords.淋巴结的功能解剖。I. 副皮质索
Int Arch Allergy Appl Immunol. 1975;48(6):836-49. doi: 10.1159/000231371.