Santamaría M, Solana R, Alonso A, Peña J
Rev Esp Fisiol. 1982 Mar;38(1):5-8.
The level of collaboration in phytohemagglutinin (PHA) induced lymphoblastic response by the macrophage of neonatal mice was studied. The results show a diminished response to the mitogen (PHA) when lymphocytes from the spleen of syngeneic adult mice were incubated in the presence of macrophages from neonatal mice as compared to those obtained from cultures performed in the presence of macrophages from adult mice. In both cases the highest response corresponded to the lowest dose of PHA and the lowest amount of macrophages used.
研究了新生小鼠巨噬细胞在植物血凝素（PHA）诱导的淋巴细胞反应中的协作水平。结果显示，与在成年小鼠巨噬细胞存在下进行的培养相比，当同基因成年小鼠脾脏中的淋巴细胞在新生小鼠巨噬细胞存在下孵育时，对丝裂原（PHA）的反应减弱。在这两种情况下，最高反应对应于最低剂量的PHA和使用的最低数量的巨噬细胞。
