Love R G, Miller B G
Thorax. 1982 Mar;37(3):193-7. doi: 10.1136/thx.37.3.193.
Longitudinal loss of lung function in 1677 coal-miners from five British collieries has been calculated from the results of serial cross-sectional epidemiological surveys and compared with measured concurrent individual respirable dust exposures and partially estimated previous cumulative exposures. Loss of forced expired volume in one second (FEV1) over approximately 11 years was found to increase with previous cumulative dust exposure after allowing for the effects of age, height, smoking, and overall colliery differences. This relationship was found to hold with concurrent dust exposure only when colliery differences were ignored. These results confirm by direct measurement inferences drawn indirectly from previous cross-sectional studies of the relationship between FEV1 and dust exposure.
根据一系列横断面流行病学调查结果，计算了来自英国五个煤矿的1677名煤矿工人的肺功能纵向损失，并将其与同时测量的个体可吸入粉尘暴露量以及部分估算的既往累积暴露量进行了比较。在考虑了年龄、身高、吸烟和煤矿总体差异的影响后，发现约11年期间一秒用力呼气量（FEV1）的损失随着既往累积粉尘暴露量的增加而增加。只有在忽略煤矿差异的情况下，才发现这种关系与同时期的粉尘暴露有关。这些结果通过直接测量证实了先前从FEV1与粉尘暴露关系的横断面研究中间接得出的推论。
