Crowther D, Wagstaff J
Clin Exp Immunol. 1983 Mar;51(3):413-20.
Studies of normal lymphocyte migratory properties in small animals and more recently in man using 111indium oxine labelling techniques are helping the clinician to understand the biology of tumours involving cells of the immune system. However, not enough is known about subset migration to interpret all the various patterns of dissemination observed in lymphoma patients. Such studies are important since they introduce new possibilities for therapy including the use of labelled cells to home a source a radiation preferentially to affected tissue.
利用111铟氧喹啉标记技术对小动物以及最近对人类正常淋巴细胞迁移特性进行的研究,正帮助临床医生了解涉及免疫系统细胞的肿瘤生物学。然而,对于亚群迁移的了解还不足以解释在淋巴瘤患者中观察到的所有不同的播散模式。此类研究很重要,因为它们为治疗带来了新的可能性,包括使用标记细胞将辐射源优先导向受影响组织。