Meuer S C, Hussey R E, Hodgdon J C, Hercend T, Schlossman S F, Reinherz E L
Science. 1982 Oct 29;218(4571):471-3. doi: 10.1126/science.6981845.
Cloned human cytotoxic T lymphocytes and monoclonal antibodies inhibiting their function (anti-T3A, anti-T4A, and anti-T8A) were used to elucidate the role of T cell surface glycoproteins in cell-mediated lympholysis involving individual classes of gene products of the major histocompatibility complex on target cells. The results indicate that several surface molecules are required for specific target recognition: T3 and T4 on T4+ cytotoxic T lymphocytes and T3 and T8 on T8+ cytotoxic T lymphocytes.
克隆的人细胞毒性T淋巴细胞和抑制其功能的单克隆抗体（抗T3A、抗T4A和抗T8A）被用于阐明T细胞表面糖蛋白在涉及靶细胞上主要组织相容性复合体个别基因产物类别的细胞介导的淋巴细胞溶解中的作用。结果表明，特异性靶细胞识别需要几种表面分子：T4⁺细胞毒性T淋巴细胞上的T3和T4，以及T8⁺细胞毒性T淋巴细胞上的T3和T8。
