Cynamon M H, Palmer G S
Antimicrob Agents Chemother. 1983 Jun;23(6):935-7. doi: 10.1128/AAC.23.6.935.
The comparative in vitro activity of cefoxitin, cephalothin, amoxicillin, and clavulanic acid in combination with the latter two agents against 13 isolates of Mycobacterium fortuitum was evaluated by agar dilution susceptibility testing. Amoxicillin was more active than cephalothin but less active than cefoxitin against the strains tested. Clavulanic acid in combination with these beta-lactams usually improved the activity by one or two dilutions compared with the beta-lactams alone.
通过琼脂稀释药敏试验评估了头孢西丁、头孢噻吩、阿莫西林以及克拉维酸(与后两种药物联合使用)对13株偶然分枝杆菌的体外比较活性。在受试菌株中,阿莫西林的活性高于头孢噻吩,但低于头孢西丁。与单独使用β-内酰胺类药物相比,克拉维酸与这些β-内酰胺类药物联合使用时,活性通常可提高1倍或2倍稀释度。