抗核抗体阴性的系统性红斑狼疮——有多常见？
Antinuclear antibody-negative systemic lupus erythematosus-how common?
作者信息
McHardy K C, Horne C H, Rennie J
出版信息
J Clin Pathol. 1982 Oct;35(10):1118-21. doi: 10.1136/jcp.35.10.1118.
Abstract
A review of five years' DNA-binding antibody results in a routine service laboratory revealed 38 patients who had high DNA-binding capacity (DNA-bc) but no antinuclear antibodies (ANA). On retrospective case note analysis, 22 patients (58%) were thought to have systemic lupus erythematosus (SLE), although only six (16%) fulfilled the preliminary classification criteria of the American Rheumatism Association (ARA). Our findings indicate that ANA-negative SLE is commoner than generally realised and lead us to recommended the measurement of DNA-bc in every case where clinically appropriate.
摘要
对一家常规服务实验室五年的DNA结合抗体检测结果进行回顾发现，有38例患者DNA结合能力（DNA-bc）高但无抗核抗体（ANA）。通过回顾性病例记录分析，22例患者（58%）被认为患有系统性红斑狼疮（SLE），尽管只有6例（16%）符合美国风湿病协会（ARA）的初步分类标准。我们的研究结果表明，ANA阴性的SLE比普遍认为的更为常见，并促使我们建议在临床合适的情况下对每例患者进行DNA-bc检测。
相似文献
1
Antinuclear antibody-negative systemic lupus erythematosus-how common?抗核抗体阴性的系统性红斑狼疮——有多常见？
J Clin Pathol. 1982 Oct;35(10):1118-21. doi: 10.1136/jcp.35.10.1118.
2
Isolated antinuclear antibody-negative lupus nephropathy in young children.幼儿孤立性抗核抗体阴性狼疮性肾炎
Child Nephrol Urol. 1988;9(6):340-6.
3
Weighted criteria for the diagnosis of systemic lupus erythematosus.
Arch Intern Med. 1984 Feb;144(2):281-5.
4
Antibodies to cytoplasmic antigens in lupus erythematosus. Serologic marker for systemic disease.红斑狼疮中针对细胞质抗原的抗体。系统性疾病的血清学标志物。
Arthritis Rheum. 1977 Nov-Dec;20(8):1457-63. doi: 10.1002/art.1780200803.
5
ANA as an entry criterion for the classification of SLE.抗核抗体作为 SLE 分类的纳入标准。
Autoimmun Rev. 2019 Dec;18(12):102400. doi: 10.1016/j.autrev.2019.102400. Epub 2019 Oct 19.
6
Relation of titred peripheral pattern ANA to anti-DNA and disease activity in systemic lupus erythematosus.系统性红斑狼疮中滴度外周型ANA与抗DNA及疾病活动度的关系
Ann Rheum Dis. 1977 Feb;36(1):44-9. doi: 10.1136/ard.36.1.44.
7
A proposed criteria for diagnosis of systemic lupus erythematosus used in Veterans General Hospital.荣民总医院使用的系统性红斑狼疮诊断建议标准。
Zhonghua Min Guo Wei Sheng Wu Ji Mian Yi Xue Za Zhi. 1982 May;15(2):87-97.
8
9
The delayed appearance of an antinuclear factor and the diagnosis of systemic lupus erythematosus in glomerulonephritis.抗核因子延迟出现与肾小球肾炎中系统性红斑狼疮的诊断
Postgrad Med J. 1979 Oct;55(648):723-7. doi: 10.1136/pgmj.55.648.723.
10
[Correlation between organic changes, antibodies against native DNA and antinuclear antibody titer in patients with systemic lupus erythematosus].
Pol Tyg Lek. 1985 Jun 10;40(23):654-6.
引用本文的文献
1
Positive Antinuclear Antibody (ANA)-Negative Systemic Lupus Erythematosus (SLE) Presenting With Acute Pancreatitis.抗核抗体（ANA）阳性、系统性红斑狼疮（SLE）阴性且伴有急性胰腺炎
Cureus. 2022 Mar 10;14(3):e23031. doi: 10.7759/cureus.23031. eCollection 2022 Mar.
2
Different indirect immunofluorescence ANA substrate performance in a diagnostic setting of patients with SLE and related disorders: retrospective review and analysis.不同间接免疫荧光抗核抗体底物在系统性红斑狼疮和相关疾病患者诊断中的性能：回顾性分析。
Lupus Sci Med. 2020 Nov;7(1). doi: 10.1136/lupus-2020-000431.
3
Pattern of antinuclear antibody and antiextractable nuclear antigen antibody test requisitions in Riyadh.利雅得抗核抗体和抗可提取核抗原抗体检测申请模式。
J Family Med Prim Care. 2019 Nov 15;8(11):3559-3564. doi: 10.4103/jfmpc.jfmpc_758_19. eCollection 2019 Nov.
4
Kozhikode criteria for diagnosing systemic lupus erythematosus as a hematological disorder.用于将系统性红斑狼疮诊断为血液系统疾病的科泽科德标准。
J Blood Med. 2016 Mar 8;7:13-8. doi: 10.2147/JBM.S95839. eCollection 2016.
5
Hematological Manifestations of SLE at Initial Presentation: Is It Underestimated?系统性红斑狼疮初发时的血液学表现：是否被低估了？
ISRN Hematol. 2012;2012:961872. doi: 10.5402/2012/961872. Epub 2012 Jul 9.
6
An antinuclear antibody-negative patient with lupus nephritis.一名抗核抗体阴性的狼疮性肾炎患者。
Korean J Intern Med. 2009 Mar;24(1):76-9. doi: 10.3904/kjim.2009.24.1.76.
7
Detection of anti-dsDNA as a diagnostic tool.检测抗双链DNA作为一种诊断工具。
Ann Rheum Dis. 1985 Aug;44(8):573-4. doi: 10.1136/ard.44.8.573-b.
本文引用的文献
1
CLINICAL MANIFESTATIONS OF SYSTEMIC LUPUS ERYTHEMATOSUS. COMPUTER ANALYSIS OF 520 CASES.系统性红斑狼疮的临床表现。520例病例的计算机分析。
JAMA. 1964 Oct 12;190:104-11. doi: 10.1001/jama.1964.03070150014003.
2
THE NATURAL HISTORY OF THE RENAL MANIFESTATIONS OF SYSTEMIC LUPUS ERYTHEMATOSUS.系统性红斑狼疮肾脏表现的自然史
J Lab Clin Med. 1964 Apr;63:537-50.
3
Diagnosis and treatment of lupus erythematosus, dermatomyositis, and scleroderma, with emphasis on cutaneous findings.红斑狼疮、皮肌炎和硬皮病的诊断与治疗，重点关注皮肤表现。
J Chronic Dis. 1961 May;13:401-10. doi: 10.1016/0021-9681(61)90026-1.
4
Variations in the morphological patterns of "autoimmune" nuclear fluorescence.“自身免疫性”核荧光形态模式的变化
Lancet. 1961 Jun 3;1(7188):1203-5. doi: 10.1016/s0140-6736(61)91944-4.
5
Systemic lupus erythematosus: review of the literature and clinical analysis of 138 cases.系统性红斑狼疮：文献综述及138例临床分析
Medicine (Baltimore). 1954 Dec;33(4):291-437.
6
Disseminated lupus erythematosus; analysis of thirty-four cases.播散性红斑狼疮；34例病例分析。
AMA Arch Intern Med. 1952 Dec;90(6):790-807. doi: 10.1001/archinte.1952.00240120065007.
7
The clinical significance of the antinuclear antibody test as a screening procedure for DNA antibodies in SLE.抗核抗体检测作为系统性红斑狼疮中DNA抗体筛查程序的临床意义。
Scott Med J. 1980 Oct;25(4):293-8. doi: 10.1177/003693308002500409.
8
Serological findings in patients with "ANA-negative" systemic lupus erythematosus.“抗核抗体阴性”系统性红斑狼疮患者的血清学检查结果
Medicine (Baltimore). 1981 Mar;60(2):87-94. doi: 10.1097/00005792-198103000-00002.
9
Antinuclear antibody-negative systemic lupus erythematosus. I. Anti-Ro(SSA) and anti-La(SSB) antibodies.
J Am Acad Dermatol. 1981 Jan;4(1):84-9. doi: 10.1016/s0190-9622(81)70013-6.
10
Measurement of serum DNA-binding activity in systemic lupus erythematosus.系统性红斑狼疮患者血清DNA结合活性的测定
N Engl J Med. 1969 Sep 25;281(13):701-5. doi: 10.1056/NEJM196909252811304.
Zotero 插件