Jarrett P E, Morland M, Browse N L
Br Med J. 1978 Aug 19;2(6136):523-5. doi: 10.1136/bmj.2.6136.523.
Twenty patients with advanced Raynaud's phenomenon, in 14 of whom it was secondary to scleroderma, were treated with stanozolol, an anabolic steroid that enhances natural fibrinolysis. All showed an increase in hand blood flow and a reduction in symptoms during treatment. This response may have been caused by the lysis of fibrin deposited in the digital arteries and the reduction of plasma viscosity. Stanozolol is a useful addition to the treatment of patients with advanced Raynaud's phenomenon who have trophic changes.
20例晚期雷诺现象患者接受了司坦唑醇治疗，其中14例继发于硬皮病，司坦唑醇是一种能增强自然纤维蛋白溶解的合成代谢类固醇。所有患者在治疗期间手部血流增加，症状减轻。这种反应可能是由于沉积在指动脉中的纤维蛋白溶解以及血浆粘度降低所致。对于有营养改变的晚期雷诺现象患者，司坦唑醇是治疗中的一种有用药物。
