梅毒螺旋体与品他密螺旋体这两种不可培养的人类病原体之间的遗传关系。
Genetic relationship between Treponema pallidum and Treponema pertenue, two noncultivable human pathogens.
作者信息
Miao R M, Fieldsteel A H
出版信息
J Bacteriol. 1980 Jan;141(1):427-9. doi: 10.1128/jb.141.1.427-429.1980.
Abstract
Genetic relationships among two strains of Treponema pallidum (Nichols and KKJ) and a strain of T. pertenue were determined by measuring the degree of deoxyribonucleic acid sequence homology. The results in indicated that these three virulent, noncultivable treponemes were genetically indistinguishable. Like T. pallidum (Nichols), T. pertenue (Gauthier) had no detectable deoxyribonucleic acid sequence homology with T. phagedenis (biotype Reiter), T. refringens (biotype Noguchi), or with salmon sperm.
摘要
通过测量脱氧核糖核酸序列同源性程度，确定了两株梅毒螺旋体（Nichols株和KKJ株）与一株雅司螺旋体之间的遗传关系。结果表明，这三种致病性、不可培养的密螺旋体在遗传上无法区分。与梅毒螺旋体（Nichols株）一样，雅司螺旋体（Gauthier株）与溃蚀性螺旋体（Reiter生物型）、致密螺旋体（野口生物型）或鲑鱼精子均未检测到脱氧核糖核酸序列同源性。
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J Bacteriol. 1980 Jan;141(1):427-9. doi: 10.1128/jb.141.1.427-429.1980.
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