Boulos P B, Whitfield P F, Dave M, Faber R G, Hobsley M
Gut. 1980 Jan;21(1):18-22. doi: 10.1136/gut.21.1.18.
One source of error in gastric secretion studies is swallowed saliva. The possibility that salivary thiocyanate might be used to measure this contamination has been investigated. Thiocyanate concentration was measured in saliva and gastric juice collected simultaneously in 22 duodenal ulcer patients undergoing routine insulin and histamine secretion studies. On stimulation, despite the increase in the rate of gastric secretion this was not matched by an appropriate fall in the concentration of thiocyanate in gastric juice. Moreover, in one-third of the gastric juice specimens, the thiocyanate concentration was greater than in the simultaneous samples of saliva. Thus, contrary to what has been claimed, thiocyanate is present not only in saliva but also in gastric juice. Therefore it cannot be used as a marker of salivary contamination. An adequate marker of this source of error has not yet been found.
胃液分泌研究中的一个误差来源是吞咽的唾液。人们对唾液硫氰酸盐能否用于测量这种污染的可能性进行了研究。在22名接受常规胰岛素和组胺分泌研究的十二指肠溃疡患者中，同时收集了唾液和胃液，并测量了其中硫氰酸盐的浓度。在刺激状态下，尽管胃液分泌速率增加，但胃液中硫氰酸盐浓度并未相应下降。此外，在三分之一的胃液样本中，硫氰酸盐浓度高于同时采集的唾液样本。因此，与所宣称的情况相反，硫氰酸盐不仅存在于唾液中，也存在于胃液中。所以它不能用作唾液污染的标志物。尚未找到这种误差来源的合适标志物。
