Schällibaum M, Nicolet J, König H
Sabouraudia. 1980 Mar;18(1):33-8.
Five cases of bovine udder aspergillosis diagnosed clinically and confirmed by repeated demonstration of fungal hyphae in KOH preparations and isolation of the organism from milk sediments are described. In one case the fungus was identified as Aspergillus nidulans, in the other 4 cases as A. fumigatus. The most pronounced features in altered udders were multiple abscesses with distinctive colonies of fungal hyphae in the centres, embedded in cell detritus, neutrophils and macrophages. These purulent centres were surrounded by varying amounts of granulation tissue. Two cases revealed purulent galactophoritis suggesting an ascending infection through the lactiferous ducts. In one case no changes of the milk ducts were observed. In this case haematogenous infection of the udder cannot be excluded.
本文描述了5例经临床诊断的牛乳房曲霉病病例，通过在氢氧化钾制剂中反复发现真菌菌丝以及从乳汁沉淀物中分离出该病原体得以确诊。其中1例真菌鉴定为构巢曲霉，另外4例为烟曲霉。乳房病变最显著的特征是出现多个脓肿，脓肿中心有独特的真菌菌丝菌落，包埋于细胞碎屑、中性粒细胞和巨噬细胞中。这些脓性中心被不同数量的肉芽组织包围。2例显示脓性输乳管炎，提示感染通过输乳管上行。1例未观察到乳管有变化。在这种情况下，不能排除乳房血源性感染。
