Emery D, McCullagh P
Transplantation. 1980;29(1):4-9. doi: 10.1097/00007890-198001000-00002.
The response of chimeric calves to grafts of cotwin skin was examined both by direct observation of the fate of the graft and by collection of lymph from the lymph node which drained the grafted area. Whilst grafts of body skin exchanged between 16 pairs of twins survived for longer periods than did grafts transferred between unrelated calves, all of the former had been rejected after 10 weeks. Secondary grafts of cotwin body skin were rejected significantly faster. In contrast, grafts of auricular skin exchanged between cotwins survived indefinitely in some instances despite the rejection of simultaneously transferred body skin. The magnitude of the blast cell response observed in efferent lymph in the case of grafts exchanged between cotwins was generally intermediate between that observed in responses to allografts and control autografts. However, an early peak of blast cell response which occurred some 50 hr after placement of allogeneic grafts was not observed in response to cotwin grafts.
通过直接观察移植皮肤的命运以及收集引流移植区域的淋巴结中的淋巴液，研究了嵌合小牛对同卵双生皮肤移植的反应。虽然16对双胞胎之间交换的身体皮肤移植比无关小牛之间移植的皮肤存活时间更长，但所有前者在10周后均被排斥。同卵双生身体皮肤的二次移植被排斥的速度明显更快。相比之下，同卵双生之间交换的耳廓皮肤移植在某些情况下可无限期存活，尽管同时移植的身体皮肤被排斥。在同卵双生之间交换移植的情况下，在传出淋巴中观察到的母细胞反应强度通常介于对同种异体移植和对照自体移植的反应之间。然而，在对同卵双生移植的反应中未观察到同种异体移植放置后约50小时出现的母细胞反应早期峰值。
