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吸入性粉末与沙丁胺醇气雾剂在哮喘儿童中的应用比较。 (注:原文中“fenoterol”有误,正确的药物名应该是“salbutamol”,译文按照正确药物名翻译)

Inhaled powder compared with aerosol administration of fenoterol in asthmatic children.

作者信息

Chambers S, Dunbar J, Taylor B

出版信息

Arch Dis Child. 1980 Jan;55(1):73-4. doi: 10.1136/adc.55.1.73.

Abstract

Fenoterol as a powdered inhalation was shown to have a longer and stronger bronchodilator effect than the same dose inhaled from a standard metered dose aerosol in a double-blind double-placebo controlled cross-over study in 13 severely asthmatic children. The powder method of administration is free from many of the disadvantages of pressurised aerosols and may prove the method of choice in childhood.

摘要

在一项针对13名重度哮喘儿童的双盲双安慰剂对照交叉研究中,与从标准定量气雾剂吸入相同剂量相比,吸入用粉雾剂形式的非诺特罗显示出更长且更强的支气管扩张作用。粉雾剂给药方法没有许多压力定量气雾剂的缺点,可能成为儿童用药的首选方法。

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引用本文的文献

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Sodium cromoglycate: spincaps or metered dose aerosol.色甘酸钠:旋帽式或定量气雾剂。
Br J Clin Pharmacol. 1981 Apr;11(4):383-4. doi: 10.1111/j.1365-2125.1981.tb01136.x.
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Salbutamol: tablets, inhalational powder, or nebuliser?沙丁胺醇:片剂、吸入粉还是雾化器?
Br Med J (Clin Res Ed). 1981 Jan 10;282(6258):105-6. doi: 10.1136/bmj.282.6258.105.

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