Lomakina L V
Ukr Biokhim Zh (1978). 1980 May-Jun;52(3):305-8.
The intensity of lipid peroxidation and the proteolytic activity were studied in two rat brain and liver fractions, supernatant and that enriched with lysosomes, at acid pH in the initial period of the medium low temperature (2-4 degrees C) effect. A short-term effect of low temperature (24h) intensifies lipid peroxidation in the brain tissue and decreases it in the liver. On the third day the level of malonic dialdehyde becomes equal to the control one. On the first day of exposure to cold the intensity of proteolysis in the supernatant fraction and that enriched with lysosomes increases sharply in the brain and liver tissues. On the third day the proteolytic activity in the supernatant fraction of the brain tissue is almost twice as high, as in the lysosome sediment, in the liver lysosomal fraction it continues increasing and in the supernatant fraction, though being lower as compared with the first day, it remains higher than in the control.
在中低温（2 - 4摄氏度）作用初期，于酸性pH条件下，对大鼠脑和肝的两个组分（上清液和富含溶酶体的组分）中的脂质过氧化强度和蛋白水解活性进行了研究。低温（24小时）的短期作用增强了脑组织中的脂质过氧化，而降低了肝脏中的脂质过氧化。第三天，丙二醛水平与对照水平相等。在暴露于寒冷的第一天，脑和肝组织中上清液组分以及富含溶酶体的组分中的蛋白水解强度急剧增加。第三天，脑组织上清液组分中的蛋白水解活性几乎是溶酶体沉淀物中的两倍，肝脏溶酶体组分中的蛋白水解活性持续增加，而上清液组分中的蛋白水解活性虽然比第一天低，但仍高于对照。
