[Effects of low temperature on lipid peroxidation and intensity of proteolysis in rat brain and liver].

The intensity of lipid peroxidation and the proteolytic activity were studied in two rat brain and liver fractions, supernatant and that enriched with lysosomes, at acid pH in the initial period of the medium low temperature (2-4 degrees C) effect. A short-term effect of low temperature (24h) intensifies lipid peroxidation in the brain tissue and decreases it in the liver. On the third day the level of malonic dialdehyde becomes equal to the control one. On the first day of exposure to cold the intensity of proteolysis in the supernatant fraction and that enriched with lysosomes increases sharply in the brain and liver tissues. On the third day the proteolytic activity in the supernatant fraction of the brain tissue is almost twice as high, as in the lysosome sediment, in the liver lysosomal fraction it continues increasing and in the supernatant fraction, though being lower as compared with the first day, it remains higher than in the control.