[Age characteristics of lipid peroxide oxidation induction in the rat liver during fasting].

The peroxide oxidation of lipids, both spontaneous and NADPH-induced, was studied in incubation of the liver homogenate postnuclear fraction for rats aged 1, 3, 12 and 24 months. Fasting increases significantly the rate of NADPH-dependent accumulation of malonic dialdehyde, the absolute growth value of which was almost the same in 1,3 and 24-month rats and higher than in the middle-aged animals. A relative increase in the lipid peroxide oxidation intensity during fasting as compared to the norm is more sharply pronounced in old rats.