Lemeshko V V, Nikitchenko Iu V, Kaliman P A
Ukr Biokhim Zh (1978). 1982 May-Jun;54(3):325-7.
The peroxide oxidation of lipids, both spontaneous and NADPH-induced, was studied in incubation of the liver homogenate postnuclear fraction for rats aged 1, 3, 12 and 24 months. Fasting increases significantly the rate of NADPH-dependent accumulation of malonic dialdehyde, the absolute growth value of which was almost the same in 1,3 and 24-month rats and higher than in the middle-aged animals. A relative increase in the lipid peroxide oxidation intensity during fasting as compared to the norm is more sharply pronounced in old rats.
在1、3、12和24月龄大鼠肝脏匀浆核后组分的孵育过程中，研究了脂质的过氧化物氧化，包括自发氧化和NADPH诱导的氧化。禁食显著提高了NADPH依赖性丙二醛积累的速率，其绝对增长值在1、3和24月龄大鼠中几乎相同，且高于中年动物。与正常情况相比，禁食期间脂质过氧化物氧化强度的相对增加在老年大鼠中更为明显。
