Rodger B, Whittingham S, Martin F I, Hawkins B R, Dawkins R L, Welborn T A
Clin Exp Immunol. 1980 Jan;39(1):125-9.
A population study on pancreatic islet cell antibodies (pica) among 3766 people from the town of Busselton, Western Australia showed that such antibodies were infrequent, the 'classical' insulin-dependent diabetes associated islet cell antibody being present in less than 0.01%. Pancreatic islet cell antibodies in this population were not associated with insulin-dependent diabetes mellitus, and ten known insulin-dependent diabetics did not have these antibodies. These results for an unselected population are in sharp contrast with those derived from studies on highly selected hospital patients.
对西澳大利亚州巴瑟尔顿镇3766人进行的一项关于胰岛细胞抗体(pica)的群体研究表明,此类抗体并不常见,与“经典”胰岛素依赖型糖尿病相关的胰岛细胞抗体出现率不到0.01%。该群体中的胰岛细胞抗体与胰岛素依赖型糖尿病无关,10名已知的胰岛素依赖型糖尿病患者并无此类抗体。这些针对未经过筛选人群的研究结果与那些对经过高度筛选的住院患者进行的研究结果形成了鲜明对比。