喂食自选饮食的泌乳大鼠乳腺中脂肪生成受损。胰岛素在体外逆转葡萄糖代谢抑制作用。
Impaired lipogenesis in mammary glands of lactating rats fed on a cafeteria diet. Reversal of inhibition of glucose metabolism in vitro by insulin.
作者信息
Agius L, Rolls B J, Rowe E A, Williamson D H
出版信息
Biochem J. 1980 Mar 15;186(3):1005-8. doi: 10.1042/bj1861005.
Abstract
In lactating rats fed on a cafeteria diet (chow plus palatable high-energy foods) the decreased glucose uptake and lipogenesis in vitro in acini correlated with the depressed mammary-gland lipogenesis in vivo. Insulin in vitro restored the rate of glucose uptake and its conversion to lipid to values approaching those for acini from rats fed on the chow diet alone.
摘要
在喂食自助餐式饮食（普通食物加美味高能食物）的泌乳大鼠中，腺泡体外葡萄糖摄取和脂肪生成的减少与体内乳腺脂肪生成的降低相关。体外胰岛素可将葡萄糖摄取率及其向脂质的转化率恢复到接近仅喂食普通食物的大鼠腺泡的水平。
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Impaired lipogenesis in mammary glands of lactating rats fed on a cafeteria diet. Reversal of inhibition of glucose metabolism in vitro by insulin.喂食自选饮食的泌乳大鼠乳腺中脂肪生成受损。胰岛素在体外逆转葡萄糖代谢抑制作用。
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