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不饱和脂肪与糖尿病视网膜病变的进展

Unsaturated fats and progression of diabetic retinopathy.

作者信息

Houtsmuller A J, Zahn K J, Henkes H E

出版信息

Doc Ophthalmol. 1980 Apr 15;48(2):363-71. doi: 10.1007/BF00141465.

DOI:10.1007/BF00141465
PMID:6995054
Abstract

Two groups of adult-onset diabetics, matched according to 10 different criteria, were followed, biochemically and fluorescein-angiographically, over a period of 6 years. One group used a saturated-fat diet, and the other group of patients were on an unsaturated-fat diet, particularly rich in linoleic acid. Statistically significant differences were found in biochemical data and in the progression of diabetic microangiopathy between the two groups. The conclusion is warranted that a linoleic acid-rich diet, administered over an extended period of time, may inhibit the development of microangiopathy, or the deterioration of diabetic retinopathy.

摘要

两组成年发病型糖尿病患者,根据10项不同标准进行匹配,在6年时间里对他们进行了生化和荧光素血管造影随访。一组采用饱和脂肪饮食,另一组患者采用不饱和脂肪饮食,特别是富含亚油酸的饮食。两组之间在生化数据和糖尿病微血管病变进展方面发现了具有统计学意义的差异。由此可以得出结论:长期食用富含亚油酸的饮食可能会抑制微血管病变的发展或糖尿病视网膜病变的恶化。

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Unsaturated fats and progression of diabetic retinopathy.不饱和脂肪与糖尿病视网膜病变的进展
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本文引用的文献

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The effect of a low fat diet on the serum lipids in diabetes and its significance in diabetic retinopathy.低脂饮食对糖尿病患者血脂的影响及其在糖尿病视网膜病变中的意义。
Am J Med. 1959 Aug;27:196-211. doi: 10.1016/0002-9343(59)90340-7.
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Fundus diabeticus. An evaluation of the preretinopathic stage.糖尿病眼底病变。视网膜病变前期的评估。
Am J Ophthalmol. 1965 Oct;60(4):662-70.
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Preliminary report on effects of photocoagulation therapy. The Diabetic Retinopathy Study Research Group.光凝疗法效果的初步报告。糖尿病视网膜病变研究组。
脂肪酸摄入与日本人群糖尿病视网膜病变的相关性。
Sci Rep. 2023 Aug 9;13(1):12903. doi: 10.1038/s41598-023-39734-x.
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Dietary Intake and Diabetic Retinopathy: A Systematic Review of the Literature.饮食摄入与糖尿病视网膜病变:文献系统综述。
Nutrients. 2022 Nov 25;14(23):5021. doi: 10.3390/nu14235021.
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Omega-6 fatty acids and the risk of cardiovascular disease: insights from a systematic review and meta-analysis of randomized controlled trials and a Mendelian randomization study.ω-6脂肪酸与心血管疾病风险:来自随机对照试验的系统评价和荟萃分析以及孟德尔随机化研究的见解
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6
Serum ω-6/ω-3 polyunsaturated fatty acids ratio and diabetic retinopathy: A propensity score matching based case-control study in China.血清ω-6/ω-3多不饱和脂肪酸比例与糖尿病视网膜病变:中国一项基于倾向评分匹配的病例对照研究。
EClinicalMedicine. 2021 Aug 16;39:101089. doi: 10.1016/j.eclinm.2021.101089. eCollection 2021 Sep.
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Cochrane Database Syst Rev. 2020 Aug 21;8(8):CD011737. doi: 10.1002/14651858.CD011737.pub3.
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Cochrane Database Syst Rev. 2020 May 19;5(5):CD011737. doi: 10.1002/14651858.CD011737.pub2.
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