Sokol S
Int Ophthalmol Clin. 1980 Spring;20(1):251-68.
The purpose of this chapter has been to demonstrate that the VEP can be used as an objective measure of visual function in infants and young children. It provides the clinician with a quantifiable index of visual impairment, and indeed may be useful in predicting a reduction of subjective visual acuity before it is found on clinical examination. There is no doubt that such abnormalities as strabismus, cataracts, ptosis, and corneal opacities can be detected on clinical examination without the aid of VEPs; however, the VEP may determine, particularly in preverbal children, whether and to what extent that abnormality has caused an impairment in acuity. The assumption is made in the case of a monocular reduction in acuity that if VEP amplitudes from the two eyes are not equal, visual acuity is not equal. This is a valid assumption since there is a correlation between reduced visual acuity and VEP amplitudes in older children with amblyopia who give reliable subjective acuities. In addition to the detection and evaluation of acuity loss in infants and children, the VEP offers a way of monitoring the efficacy of occlusion therapy and CAM therapy. Also the VEP can be used to monitor the effects of corneal and lens opacities on visual development.
本章的目的是证明视觉诱发电位（VEP）可作为婴幼儿视觉功能的一种客观测量方法。它为临床医生提供了一个可量化的视力损害指标，实际上在临床检查发现之前，可能有助于预测主观视力的下降。毫无疑问，诸如斜视、白内障、上睑下垂和角膜混浊等异常情况在不借助VEP的临床检查中即可被检测到；然而，VEP尤其在尚不能言语的儿童中，可以确定该异常是否以及在何种程度上导致了视力损害。对于单眼视力下降的情况，我们的假设是，如果两眼的VEP振幅不相等，那么视力也不相等。这是一个有效的假设，因为在能够给出可靠主观视力的大龄弱视儿童中，视力下降与VEP振幅之间存在相关性。除了检测和评估婴幼儿及儿童的视力丧失情况外，VEP还提供了一种监测遮盖疗法和CAM疗法疗效的方法。此外，VEP可用于监测角膜和晶状体混浊对视觉发育的影响。
