Lal S, Malhotra S M, Gribben M D, Butler A G
Clin Allergy. 1980 May;10(3):259-62. doi: 10.1111/j.1365-2222.1980.tb02105.x.
In a double-blind trial, beclomethasone dipropionate inhaled as a dry powder in doses of 200 micrograms three times a day was compared with the conventional aerosol of 100 micrograms three times a day, each for a period of 4 weeks. Neither the dry powder nor the aerosol showed any significant advantage over each other in terms of ventilatory function. Plasma cortisol levels were unaltered with the two medications in spite of the doubled dose of the corticosteroid powder. Choice of one or the other method of administration of medication depended on patient preference and the ease with which he could familiarize himself with either technique.
在一项双盲试验中,将每日三次吸入剂量为200微克的丙酸倍氯米松干粉与每日三次吸入100微克的传统气雾剂进行比较,每组为期4周。就通气功能而言,干粉和气雾剂均未显示出任何显著优势。尽管皮质类固醇粉末剂量加倍,但两种药物对血浆皮质醇水平均无影响。选择哪种给药方法取决于患者的偏好以及他熟悉每种技术的难易程度。