丙酸倍氯米松通过压力定量气雾剂和旋转式吸入器干粉给药的临床比较。
A clinical comparison of beclomethasone dipropionate delivered by pressurised aerosol and as a powder from a rotahaler.
作者信息
Edmunds A T, McKenzie S, Tooley M, Godfrey S
出版信息
Arch Dis Child. 1979 Mar;54(3):233-5. doi: 10.1136/adc.54.3.233.
Abstract
14 children with severe asthma were studied for 2 months in a double-blind cross-over trial to compare the efficacy of beclomethasone dipropionate delivered as an aerosol and as a powder from a rotahaler. Inhalation via the aerosol was satisfactory in 13 patients, each of whom used the rotahaler correctly. Younger children preferred to use the rotahaler. Comparison of daily symptoms, twice daily peak expiratory flow rate (PEFR), and use of salbutamol during the 2 months of the trial showed that control of asthma was equally good, irrespective of the device used to deliver active beclomethasone.
摘要
在一项双盲交叉试验中，对14名重度哮喘患儿进行了为期2个月的研究，以比较二丙酸倍氯米松气雾剂和旋转式吸入器干粉剂的疗效。13名患者通过气雾剂吸入效果良好，且每人都能正确使用旋转式吸入器。年幼患儿更喜欢使用旋转式吸入器。在试验的2个月期间，对每日症状、每日两次的呼气峰值流速（PEFR）以及沙丁胺醇的使用情况进行比较，结果表明，无论使用何种装置来递送活性二丙酸倍氯米松，哮喘的控制效果都同样良好。
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