Cassar J, Kohner E M, Hamilton A M, Gordon H, Joplin G F
Diabetologia. 1978 Aug;15(2):105-11. doi: 10.1007/BF00422254.
Diabetic retinopathy was found to be present in 12 out of a group of 67 diabetic patients supervised by us during 92 pregnancies, and 3 further pregnant diabetics were referred to us because of retinopathy. The mean duration of diabetes was 13 years (range 3--25 years). Nine patients had minimal retinopathy, 2 had background retinopathy, and the remaining 4 proliferative retinopathy. The cases with minimal retinopathy showed no progression during pregnancy. In 1 patient with background retinopathy there was deterioration. Of the 4 patients with proliferative retinopathy 1 showed regression during the pregnancy, 2 showed advance and were treated with photocoagulation (these 2 patients now have normal vision), while the patient with extensive retinitis proliferans, with retinal detachment in both eyes and previous photocoagulation remained unchanged. The prognosis during pregnancy for patients with diabetic retinopathy is reasonable and has been improved by the advent of photocoagulation.
在我们所监护的67例糖尿病患者的92次妊娠过程中,发现12例患有糖尿病性视网膜病变,另有3例妊娠糖尿病患者因视网膜病变转诊至我们这里。糖尿病平均病程为13年(范围3 - 25年)。9例患者有轻度视网膜病变,2例有背景性视网膜病变,其余4例为增殖性视网膜病变。轻度视网膜病变的患者在妊娠期间病情无进展。1例背景性视网膜病变患者病情恶化。4例增殖性视网膜病变患者中,1例在妊娠期间病情好转,2例病情进展并接受了光凝治疗(这2例患者现在视力正常),而双眼视网膜广泛增殖、视网膜脱离且之前已接受光凝治疗的患者病情无变化。糖尿病性视网膜病变患者妊娠期间的预后是合理的,并且光凝治疗的出现改善了预后。