Horvat M, Maclean H, Goldberg L, Crock G W
Br J Ophthalmol. 1980 Jun;64(6):398-403. doi: 10.1136/bjo.64.6.398.
A prospective study extending over 12 years has surveyed 107 latent diabetics and 172 clinical diabetics during pregnancy. Among the clinical diabetics background retinopathy was evident or developed during pregnancy in 40 cases. Eleven cases showed proliferative changes, only 1 such case appearing de novo during gestation. There was a higher incidence of fetal loss in the diabetic than the latent diabetic group, and this loss was highest in those with proliferative retinal disease. Pregnancy was to associated with any increased risk to the mother of progression of retinal changes and visual loss. The only known direct relationship, namely, that between duration of diabetes and ocular complications, is confirmed.
一项为期12年的前瞻性研究对107例妊娠潜伏性糖尿病患者和172例临床糖尿病患者进行了调查。在临床糖尿病患者中，40例在妊娠期间出现明显的背景性视网膜病变或病变进展。11例出现增殖性改变，其中仅1例在妊娠期新发。糖尿病组的胎儿丢失率高于潜伏性糖尿病组，且在增殖性视网膜病变患者中胎儿丢失率最高。妊娠与母亲视网膜病变进展和视力丧失风险增加无关。唯一已知的直接关系，即糖尿病病程与眼部并发症之间的关系，得到了证实。
