Kozin F, Fowler M, Koethe S M
Am J Clin Pathol. 1980 Dec;74(6):785-90. doi: 10.1093/ajcp/74.6.785.
Six different commercially available substrates for fluorescent antinuclear antibody (FANA) testing were compared with mouse liver, using a panel of well--characterized sera. Mouse liver sections and cultured HEP2 cells appeared to be most sensitive and specific. Although most substrates were acceptable, several were quite insensitive. These results underscore the importance of substrate performance in FANA testing.
使用一组特征明确的血清，将六种不同的市售荧光抗核抗体（FANA）检测底物与小鼠肝脏进行了比较。小鼠肝脏切片和培养的HEP2细胞似乎最敏感且特异。虽然大多数底物是可接受的，但有几种相当不敏感。这些结果强调了底物性能在FANA检测中的重要性。
