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对氨苄青霉素、四环素、磺胺类药物和甲氧苄啶耐药的鼠伤寒沙门氏菌179型噬菌体的质粒研究。

Plasmid studies of Salmonella typhimurium phage type 179 resistant to ampicillin, tetracycline, sulphonamides and trimethoprim.

作者信息

Anderson D M

出版信息

J Hyg (Lond). 1980 Oct;85(2):293-300. doi: 10.1017/s0022172400063336.

DOI:10.1017/s0022172400063336
PMID:7005330
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2133935/
Abstract

Sixteen strains of Salmonella typhimurium phage type 179 were referred to the National Health Institute, Wellington, New Zealand, from 1977 to 1979. This phage type had not been observed here before 1977. All strains were resistant to ampicillin, several were also resistant to tetracycline, and several were resistant to ampicillin, tetracycline, sulphafurazole and trimethoprim. All resistances could be transferred to Escherichia coli K 12. Plasmids from these strains and their transconjugants were characterized by agarose gel electrophoresis. It appears that resistance to sulphafurazole and trimethoprim is carried on a plasmid with a molecular weight of 5 . 2 Mdal and that resistance to ampicillin and tetracycline is carried on a plasmid with a molecular weight of approximately 60 Mdal.

摘要

1977年至1979年间,16株鼠伤寒沙门氏菌179型菌株被送往新西兰惠灵顿的国家卫生研究所。1977年以前在此地未曾观察到这种噬菌体类型。所有菌株对氨苄青霉素耐药,有几种还对四环素耐药,还有几种对氨苄青霉素、四环素、磺胺异恶唑和甲氧苄啶耐药。所有耐药性均可转移至大肠杆菌K12。通过琼脂糖凝胶电泳对这些菌株及其转接合子的质粒进行了鉴定。看来对磺胺异恶唑和甲氧苄啶的耐药性由一个分子量为5.2兆道尔顿的质粒携带,而对氨苄青霉素和四环素的耐药性由一个分子量约为60兆道尔顿的质粒携带。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1fd8/2133935/951ef1dbffad/jhyg00038-0133-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1fd8/2133935/951ef1dbffad/jhyg00038-0133-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1fd8/2133935/951ef1dbffad/jhyg00038-0133-a.jpg

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本文引用的文献

1
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J Gen Microbiol. 1972 Sep;72(2):349-55. doi: 10.1099/00221287-72-2-349.
2
Antibiotic sensitivity testing. Report of an international collaborative study.抗生素敏感性试验。一项国际合作研究报告。
Acta Pathol Microbiol Scand B Microbiol Immunol. 1971;217:Suppl 217:1+.
3
Translocation of the tetracycline resistance determinant from R100-1 to the Escherichia coli K-12 chromosome.四环素抗性决定因子从R100 - 1转移至大肠杆菌K - 12染色体。
新西兰和澳大利亚179型鼠伤寒沙门氏菌分离株之间的菌苔不相容性研究。
J Hyg (Lond). 1981 Jun;86(3):353-6. doi: 10.1017/s0022172400069102.
4
Transferable resistance to trimethoprim in enteric pathogens isolated in Kuwait.科威特分离出的肠道病原体对甲氧苄啶的可转移性耐药性。
J Hyg (Lond). 1985 Oct;95(2):391-5. doi: 10.1017/s0022172400062811.
J Bacteriol. 1975 Dec;124(3):1153-8. doi: 10.1128/jb.124.3.1153-1158.1975.
4
Analysis of restriction fragments of T7 DNA and determination of molecular weights by electrophoresis in neutral and alkaline gels.T7 DNA限制性片段分析及通过中性和碱性凝胶电泳测定分子量
J Mol Biol. 1977 Feb 15;110(1):119-46. doi: 10.1016/s0022-2836(77)80102-2.
5
Simple agarose gel electrophoretic method for the identification and characterization of plasmid deoxyribonucleic acid.用于鉴定和表征质粒脱氧核糖核酸的简易琼脂糖凝胶电泳方法。
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6
Application of agarose gel electrophoresis to the characterization of plasmid DNA in drug-resistant enterobacteria.琼脂糖凝胶电泳在耐药性肠道杆菌质粒DNA特征分析中的应用
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7
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